Table 1 Baseline Characteristics of IPF patients and controls in training cohort
Characteristics | Freiburg cohort (n = 62) | Siena cohort (n = 50) | Control cohort (n = 20) |
|---|---|---|---|
Age, yr | 67.4 ± 9.1 | 68.7 ± 11.2 | 61.9 ± 7.6 |
Male sex, % | 85 | 80 | 75 |
FVC % predicted value, % | 66 ± 20 | 67 ± 23 | 96 ± 19 |
DLCO | |||
Percent predicted value, % | 44 ± 16 | 40 ± 15 | – |
Could not perform DlCO, n | 7 | 12 | – |
Deaths, n (%) | 45 (73) | 31 (62) | – |
Transplants, n (%) | 3 (5) | 4 (8) | – |
Median observation time, mo | 20 | 16 | – |
Smoking status, % | |||
Never smoked | 42 | 34 | 30 |
Former smoker | 56 | 64 | 70 |
Current smoker | 2 | 2 | 0 |
HRCT UIP, n (%) | |||
Definite | 43 (69) | 38 (76) | – |
Possible | 19 (31) | 12 (24) | – |
HRCT emphysema present, n | 5 (8) | 3 (6) | – |
GAP index, n (%) | |||
Stage I | 17 (27) | 14 (28) | – |
Stage II | 32 (52) | 20 (40) | – |
Stage III | 13 (21) | 16 (32) | – |