Table 1 Demographic, clinical and functional characteristics
Variables | n = 48 |
|---|---|
Male | 33 (69) |
Age, years | 27.8 ± 8.1 |
BMI, kg/m² | 21.8 ± 3.3 |
Smoker | 5 (10) |
Active/ Ex smoker | 2 (4) / 3 (6) |
Pack-years in active/ex-smoker | 7 ± 12 |
CFTR mutation | |
ΔF508 homozygous | 20 (42) |
ΔF508 heterozygous | 24 (50) |
Other | 4 (8) |
Pancreatic insufficiency | 38 (79) |
Diabetes | 16 (33) |
Osteoporosis | 6 (12) |
Dyspnea | 26 (54) |
mMRC ≥ 2 | 9 (19) |
Exacerbation in the last year | 33 (69) |
Number of episodes per patient | 1.5 ± 1.5 |
FEV1, % predicted | 64 ± 30 |
6-minute walking test | |
Distance, m | 561 ± 88 |
Distance, % predicted | 80 |