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Table 1 Characteristics of individual studies

From: Effects of pulmonary air leak on patients with coronavirus disease 2019 (COVID-19): a systematic review and meta-analysis

Author

Country

Year

Study design

Adult

(≥ 18)

All need MV

All need ICU

Diagnosis method of COVID-19

Diagnosis method of PAL

Types of PAL

Geraci et al. [12]

USA

2021

retrospective

yes

no

no

RT-PCR

XR/CT

pneumothorax

Malik et al. [15]

USA

2022

retrospective

yes

no

no

RT-PCR

NA

pneumothorax

Pierre et al. [16]

USA

2022

retrospective

NA

no

no

NA

XR/CT

pneumothorax

Akram et al. [17]

Qatar

2022

retrospective

≥ 14

no

yes

RT-PCR

XR/CT/lung ultrasound

pneumothorax

Miro et al. [18]

Spain

2020

retrospective

NA

NA

no

RT-PCR

XR/CT

pneumothorax

Berg et al. [19]

USA

2021

retrospective

yes

no

yes

NA

XR/CT

Pneumothorax

Chopra et al. [20]

USA

2021

retrospective

yes

yes

yes

RT-PCR

NA

pneumothorax

Ozdemir et al. [21]

Turkey

2020

retrospective

yes

yes

yes

RT-PCR

XR/CT/lung ultrasound

pneumothorax

Capaccione et al. [22]

USA

2021

retrospective

NA

yes

NA

NA

XR

pneumothorax

Taha et al. [23]

USA

2022

retrospective

yes

yes

yes

RT-PCR

NA

pneumothorax

Reis et al. [24]

USA

2021

retrospective

NA

no

no

RT-PCR

XR

pneumomediastinum

Arciniega et al. [25]

Mexico

2021

retrospective

yes

no

no

RT-PCR

CT

pneumomediastinum

Ozdemir et al. [26]

Turkey

2021

retrospective

yes

yes

yes

RT-PCR

XR/CT

pneumomediastinum

Ozsoy et al. [27]

Turkey

2021

retrospective

NA

NA

NA

NA

CT

pneumomediastinum

Baslas et al. [28]

UK

2022

retrospective

yes

no

NA

RT-PCR/CT

CT

pneumomediastinum

Loffi et al. [29]

Italy

2020

retrospective

NA

no

no

RT-PCR

CT

pneumomediastinum

Righetti et al. [30]

Italy

2022

NA

NA

yes

yes

NA

NA

pneumomediastinum

Muhammad et al. [31]

UK

2022

retrospective

yes

no

no

RT-PCR

XR/CT

pneumothorax/pneumomediastinum

Tetaj et al. [32]

Italy

2021

retrospective

NA

yes

NA

RT-PCR

CT

pneumothorax/pneumomediastinum

Udwadia et al. [33]

India

2021

retrospective

NA

NA

yes

NA

XR/CT

pneumothorax/pneumomediastinum

Gazivoda et al. [34]

USA

2021

retrospective

NA

yes

yes

RT-PCR

XR

pneumothorax/pneumomediastinum

Belletti et al. [35]

Italy

2021

retrospective

yes

yes

yes

RT-PCR

XR/CT

pneumothorax/pneumomediastinum

Ernst et al. [36]

USA

2021

retrospective

NA

no

no

RT-PCR

NA

pneumothorax/pneumomediastinum

Bonato et al. [37]

Italy

2021

retrospective

NA

no

NA

RT-PCR

XR/CT

pneumothorax/pneumomediastinum

Tonelli et al. [38]

Italy

2022

retrospective

NA

yes

yes

RT-PCR

CT

pneumothorax/pneumomediastinum

Marza et al. [39]

Romania

2022

retrospective

yes

no

no

RT-PCR

XR/CT

pneumothorax/pneumomediastinum

Shaikh et al. [40]

Qatar

2021

retrospective

yes

NA

yes

NA

XR/CT

pneumothorax/pneumomediastinum

Lemmers et al. [41]

Italy

2020

retrospective

yes

yes

yes

RT-PCR

XR/CT

pneumomediastinum/subcutaneous emphysema

Steinberger et al. [42]

USA

2022

retrospective

yes

yes

NA

RT-PCR

XR/CT

pneumomediastinum/subcutaneous emphysema

Nespoli et al. [43]

Italy

2020

retrospective

NA

NA

yes

NA

XR/CT/lung ultrasound

pneumothorax/pneumomediastinum/subcutaneous emphysema

Hamouri et al. [44]

Jordan

2021

retrospective

yes

yes

no

RT-PCR

XR

pneumothorax/pneumomediastinum/subcutaneous emphysema

Guven et al. [45]

Turkey

2021

retrospective

yes

yes

no

RT-PCR

XR/CT

pneumothorax/pneumomediastinum/subcutaneous emphysema

Jones et al. [46]

UK

2020

retrospective

NA

yes

yes

RT-PCR

XR

pneumothorax/pneumomediastinum/subcutaneous emphysema

Venkateswaran et al. [47]

India

2022

retrospective

yes

yes

yes

NA

XR/CT

pneumothorax/pneumomediastinum/subcutaneous emphysema

Sami et al. [48]

Iran

2022

retrospective

NA

yes

yes

RT-PCR

XR/CT

pneumothorax/pneumomediastinum/subcutaneous emphysema

  1. COVID-19: coronavirus disease 2019, MV: mechanical ventilation, ICU: intensive care unit, PAL: pulmonary air leak, RT-PCR: reverse transcriptase-polymerase chain reaction, CT: computed tomography, XR: X-ray, NA: not applicable, USA: United States of America, UK: United Kingdom