Table 4 Multivariable logistic regression analysis to predict benign nodules in training set

Lesion type

 Part-solid nodules

0.14(0.06–0.37)

 < .001

 Non-solid nodules

0.05(0.02–0.14)

 < .001

 Lesion size at imaging, in mm

0.88(0.77–1.00)

.046

Imaging finding

 Spiculation

0.64(0.27–1.52)

.314

 Vascular convergence

0.60(0.23–1.59)

.306

 Vacuolar sign

1.27(0.56–2.89)

.567

Biomarker^a

 CYFRA21-1 status (n = 297)

  Positive

1.27(0.59–2.75)

.545