Table 1 Baseline characteristics

Age in years, median (de)

42 (9.91)

45.5 (9.44)

40 (9.97)

0.007*

Male, n (%)

108 (71.05%)

45 (77.59%)

63 (67.02%)

0.163

Weight Kg, median (de)

85.5 (17.08

86.1 (16.59)

85.2 (17.47)

0.761

Body mass index, kg/cm2 median (de)

29.7 (5.15)

29.8 (5.22)

29.6 (5.13)

0.817

Days in ICU - M (RIC)

24.1 (13.4–39.9)

14.4 (6.8–26.7)

30.5 (18.8–48.2)

< 0,001*

Days in mechanical ventilation

17.4 (10.5–26.7)

15.4 (8.77–23.3)

19 (12.9–27.2)

0.669

Days hospitalized

29(16–51)

17 (8–29)

39 (25–57)

0,005*

 Arterial hypertension

28 (18.4%)

13 (22.4%)

15(15.9%)

0.319

 Diabetes

22 (14.4%)

7 (12.1%)

15 (15.9%)

0.508

 Dislypidemia

6 (3.9%)

2 (3.4%)

4 (4.2%)

0.804

 Asthma

8 (5.2%)

4(6.9%)

4 (4.2%)

0.479

 Active smoker

7 (4.6%)

3 (5.1%)

4 (2%)

0.793

 Potassium meq/l

4.01 (0.96)

3.78 (1.27)

4.15(0.66)

0.044*

 Creatinine mg/dl

1.60(3.82)

1.54 (1.16)

1.64 (4.78)

0.847

 Ureic nitrogen

27.8 (18.9)

30.8 (19.61)

26 (18.3)

0.134

 Infection, n (%)

 SARS-CoV-2

117(76.9%)

48(82.7)

69(73.4%)

0.183

Mode of Support (%)

0.881

 Venovenous ECMO

115(75.6%)

44 (75.8%)

71 (75.5%)

 Venoarterial ECMO

33 (21.7%)

13 (22.4%)

20 (21.2%)

 Venoarteriovenous ECMO

4 (2.7%)

1 (1.72%)

3 (3.19%)

Membranes, n (%)

0.118

 Sorin

73(48%)

22(37.9%)

51(54.2%)

 Euroset

47(30.9%)

20(34.4%)

27(28.7%)

 Polypropilane-Inspire

32 (21%)

16(27,5%)

16(17%)

Severity score M (RIC)

 SOFA Score

7(5–9)

8(6–11)

7(4–9)

0,101

 APACHE II Score

9(5.5–14)

11 (6–17)

8 (5–12)

< 0,001*

 Oxygen debt DEOx

“- 1.16((−13.2) -10.8)

5.01 ((−9.8)-12.8)

“-4.44((−15.2)-6.67)

< 0,001*

 RESP

3(2–4)

2(1–4)

4(2–5)

0.255

 SAVE

0(−3 a 0)

0 (−2 a 1)

“-5 (−3–0)

0.494

Complications, n (%)

 Mechanical

34 (22.3%)

13(22.4%)

21(22.3%)

0.647

 Mayor bleeding

20 (13.1%)

10(17.2%)

10(10.6%)

0.242

 Neurological

27(17.7%)

20(34.4%)

7(7.4%)

< 0,001*

 Cardiovascular

18(11.8%)

11(18.9%)

7(7.4%)

0.033*

 Renal

39(25.6%)

21(36.2%)

18(19.1%)

0.019*

 Infection

115(75%)

29(67.7%)

76(80.8%)

0.05*

 Oxigenator failure

22(14.4%)

8(13.7%)

14(14.8%)

0.85

 Delirium

83(54.6%)

13(2.4%)

70(74.4%)

< 0,001*

 Renal replacement therapy

62(40.7%)

24(41.3%)

38(40.4%)

0.97