Table 2 Association between the presence of comorbidities according to the non-adjusted Charlson index and COPD clinical control criteria

Charlson index, n (%)

4801 (100.0)

1322 (100.0)

3479 (100.0)

Mean (SD)

2.17 (1.54)

1.90 (1.35)

2.28 (1.6)

< 0.0001

 Myocardial infarction

484 (10.1)

128 (9.7)

356 (10.2)

0.5714

1.03 (0.83–1.28); p = 0.7968

 Congestive heart failure

558 (11.6)

95 (7.2)

463 (13,3)

< 0.0001

1.83 (1.45–2.31); p < 0.0001

 Peripheral vascular disease

498 (10.4)

89 (6.7)

409 (11.8)

< 0.0001

1.80(1.41–2.29); p < 0.0001

 Cerebrovascular disease

239 (5.0)

51 (3.9)

188 (5.4)

0.0278

1.32 (0.96–1.82); p = 0.0856

 Dementia

49 (1.0)

4 (0.3)

45 (1.3)

0.0023

3.85 (1.38–10.79); p = 0.0102

 Pathology of connective tissue

73 (1.5)

14 (1.1)

59 (1.7)

0.1072

1.74 (0.96–3.14); p = 0.0664

 Ulcer disease

191 (4.0)

41 (3.1)

150 (4.3)

0.0553

1.32 (0.93–1.88); p = 0.1239

 Mild liver pathology

220 (4.6)

49 (3.7)

171 (4.9)

0.0736

1.42 (1.02–1.97); p = 0.0353

 Diabetes

1023 (21.3)

250 (18.9)

773 (22.2)

0.0124

1.22 (1.04–1.44); p = 0.0138

 Diabetes with organic lesion

173 (3.6)

24 (1.8)

149 (4.3)

< 0.0001

2.33 (1.50–3.61); p = 0.0002

 Hemiplegia

18 (0.4)

3 (0.2)

15 (0.4)

0.4298^f

1.86 (0.53–6.50); p = 0.3299

 Renal pathology (moderate or severe)

219 (4.6)

49 (3.7)

170 (4.9)

0.0801

1.22 (0.88–1.70); p = 0.2297

 Solid neoplasm without metastasis

448 (9.3)

103 (7.8)

345 (9.9)

0.0237

1.21 (0.96–1.52); p = 0.1134

 Leukemia

18 (0.4)

3 (0.2)

15 (0.4)

0.4298^f

1.77 (0.51–6.19); p = 0.3686

 Malignant lymphoma

18 (0.4)

2 (0.2)

16 (0.5)

0.1834^f

3.10 (0.71–13.52); p = 0.1324

 Liver pathology (moderate or severe)

73 (1.5)

13 (1.0)

60 (1.7)

0.0608

1.89 (1.03–3.48); p = 0.0408

 Solid metastasis

18 (0.4)

3 (0.2)

15 (0.4)

0.4298^f

1.97 (0.56–6.87); p = 0.2880

 AIDS

30 (0.6)

7 (0.5)

23 (0.7)

0.6052

1.46 (0.62–3.44); p = 0.3925