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Fig. 4 | BMC Pulmonary Medicine

Fig. 4

From: Tumor-derived KLK8 predicts inferior survival and promotes an immune-suppressive tumor microenvironment in lung squamous cell carcinoma

Fig. 4

Pathway enrichment of patients with different KLK8 expression levels in LUSC public data. a-b Representative pathways highly enriched in KLK8 low expression patients (a) and KLK8 high expression patients (b) based on the GEO LUSC datasets (GSE73403, GSE15011, GSE3021). c Representative GO terms and pathways enriched in DEGs between high and low KLK8 expression groups based on the GEO LUSC datasets (GSE73403, GSE15011, GSE3021). d Representative KEGG [25,26,27] terms and pathways enriched in DEGs between high and low KLK8 expression groups based on the GEO LUSC datasets (GSE73403, GSE15011, GSE3021). e-f Representative pathways highly enriched in KLK8 low expression patients (a) and KLK8 high expression patients (b) based on the TCGA LUSC data. g Representative GO terms and pathways enriched in DEGs between high and low KLK8 expression groups based on the TCGA LUSC data. h Representative KEGG [25,26,27] terms and pathways enriched in DEGs between high and low KLK8 expression groups based on the TCGA LUSC data

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