Table 2 Univariate Cox regression of prognostic factors in SqCLC
| Â | OS | |
|---|---|---|
HR (95%CI) | p-value | |
Sex | Â | Â |
 Female | 1.000 |  |
 Male | 1.43 (0.45–4.53) | 0.534 |
Age | Â | Â |
 ≤60 | 1.000 |  |
 > 60 | 1.34 (0.92–1.96) | 0.122 |
Smoking | Â | Â |
 No | 1.000 |  |
 Yes | 1.17 (0.54–2.52) | 0.681 |
Grade | Â | Â |
 Low | 1.000 |  |
 Mid-high | 1.41 (0.97–2.06) | 0.067 |
Tumor size | Â | Â |
 ≤5 | 1.000 |  |
 > 5 | 1.78 (1.22–2.58) | 0.002 |
T stage | Â | Â |
 T1 + T2 | 1.000 |  |
 T3 + T4 | 2.77 (1.9–4.04) | < 0.001 |
N Stage | Â | Â |
 N0 + N1 | 1.000 |  |
 N2 | 2.44 (1.67–3.57) | < 0.001 |
CD47 expression | Â | Â |
 Low | 1.000 |  |
 High | 1.81 (1.19–2.73) | 0.005 |
PDL1 expression | Â | Â |
 Low | 1.000 |  |
 High | 1.51 (1.01–2.25) | 0.044 |
PDL1&CD47 expression | Â | Â |
 Low | 1.000 |  |
 High | 1.62 (1.07–2.44) | 0.021 |
CD8 expression | Â | Â |
 Low | 1.000 |  |
 High | 0.63 (0.43–0.93) | 0.019 |
CD68 expression | Â | Â |
 Low | 1.000 |  |
 High | 1.22 (0.81–1.82) | 0.331 |
PD1 expression | Â | Â |
 Low | 1.000 |  |
 High | 1.55 (1.06–2.26) | 0.023 |
TIGIT expression | Â | Â |
 Low | 1.000 |  |
 High | 1.53 (1.05–2.22) | 0.025 |
PVR expression | Â | Â |
 Low | 1.000 |  |
 High | 1.94 (1.03–3.62) | 0.037 |
KLK8 expression | Â | Â |
 Low | 1.000 |  |
 High | 1.92 (1.31–2.81) | < 0.001 |