Association of GAB1 gene with asthma susceptibility and the efficacy of inhaled corticosteroids in children

BMC Pulmonary Medicine

Table 2 Baseline characteristics of the subjects

Description	Asthmatics	Controls	p
Anthropometry
Biological sex, n (%)
Males	77(70.64)	99(62.66)	0.176
Females	32(29.36)	59(37.34)	0.176
Age, median (IQR),year	6(4,8)	6(4,8)	0.383
BMI, median (IQR), kg/m²	16.07(15.17,18.53)	15.74(12.13,16.66)	0.015
Exposure factors
Feeding patterns, n (%)
Artificial/mixed feeding	86(78.90)	129(81.65)	0.578
Breastfeeding	23(21.10)	29(18.35)	0.578
Allergen exposure, n (%)
Yes	75(68.81)	15(9.49)	< 0.001
No	34(31.19)	143(90.51)	< 0.001
ETS exposure, n (%)
Yes	29(26.61)	9(5.70)	< 0.001
No	80(73.39)	149(94.30)	< 0.001
Pet exposure, n (%)
Yes	27(24.77)	34(21.52)	0.534
No	82(75.23)	124(78.48)	0.534
Residence, n (%)
Urban	75(68.81)	83(52.53)	0.008
Rural	34(31.19)	75(47.47)	0.008
Laboratory indices
EOS(%)	5.00 ± 5.52		NA
IgE(IU/ml)	256.86 ± 390.27		NA
Spirometry
FVC% pred^a	92.12 ± 22.30		NA
FEV1 (%)^a	83.90 ± 17.59		NA
FEV1/FVC^a	78.87 ± 12.28		NA
PEF% pred^a	68.11 ± 18.41		NA
FEF25% pred^a	66.36 ± 20.94		NA
FEF50% pred^a	61.44 ± 24.49		NA
FEF75% pred^a	52.46 ± 26.90		NA
MMEF% pred^a	58.50 ± 24.55		NA

Comparison of biological sex and exposure factors between two groups used χ² test, while age and BMI used Mann-Whitney test. The values p < 0.05 were in bold
Abbreviations: ETS environmental tobacco smoke, BMI body mass index
^aBaseline pulmonary function of asthmatic children aged ≥5 years

ISSN: 1471-2466