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Table 5 Association results between genetic variants in GAB1 gene, and percentage of EOS and IgE levels

From: Association of GAB1 gene with asthma susceptibility and the efficacy of inhaled corticosteroids in children

SNVs

Genotypes

EOS (%)

pa

IgE(IU/ml)

pb

rs1396527

     
 

G/G

3.00(1.30–5.60)

0.007

2.08 ± 0.60

0.848

 

G/T

5.50(2.50–7.70)

2.14 ± 0.51

 

T/T

3.70(2.20–6.70)

2.18 ± 0.46

rs17017425

     
 

T/T

3.10(1.60–6.40)

0.102

2.04 ± 0.50

0.390

 

C/T

4.80(2.20–7.60)

2.20 ± 0.58

 

C/C

6.80(3.90–8.30)

2.12 ± 0.59

rs1866756

     
 

G/G

3.30(1.60–6.20)

0.136

2.09 ± 0.58

0. 846

 

G/A

4.80(2.60–7.18)

2.14 ± 0.50

 

A/A

2.40(0.63–11.53)

2.22 ± 0.58

rs3805236

     
 

A/A

3.50(1.60–6.15)

0.309

2.09 ± 0.58

0.877

 

A/G

4.45(2.40–7.18)

2.15 ± 0.52

 

G/G

4.80(2.50–14.50)

2.10 ± 0.41

rs3805246

     
 

G/G

3.50(1.60–6.48)

0.240

2.10 ± 0.58

0. 064

 

G/A

4.80(2.50–6.80)

2.13 ± 0.50

 

A/A

2.40(0.63–11.53)

2.22 ± 0.58

rs3805254

     
 

A/A

3.50(1.60–6.48)

0.240

2.10 ± 0.58

0. 064

 

A/G

4.80(2.50–6.80)

2.13 ± 0.50

 

G/G

2.40(0.63–11.53)

2.22 ± 0.58

  1. The values p < 0.05 were in bold
  2. Abbreviations: a Kruskal-Wallis H test for EOS distribution between genotypes in the asthma group; b ANOVA for lg (lgE) distribution between genotypes in the asthma group