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Table 6 Association between GAB1gene SNVs and change in FEV1/FVC after ICS treatment

From: Association of GAB1 gene with asthma susceptibility and the efficacy of inhaled corticosteroids in children

SNVs

Genotypes

Change in FEVI/FVC (%)

p

pa

pb

rs1396527

     
 

G/G

14.84 ± 12.13

0.032

0.009

0.593

 

G/T

7.93 ± 9.49

 

T/T

8.31 ± 8.31

rs17017425

     
 

T/T

12.26 ± 8.94

0.366

0.220

0.270

 

C/T

9.71 ± 14.08

 

C/C

6.10 ± 10.13

rs1866756

     
 

G/G

12.89 ± 12.14

0.273

0.109

0.585

 

G/A

8.80 ± 9.50

 

A/A

7.44 ± 9.50

rs3805236

     
 

A/A

13.75 ± 11.51

0.061

0.025

0.262

 

A/G

8.26 ± 9.99

 

G/G

2.21 ± 4.05

rs3805246

     
 

G/G

12.89 ± 12.14

0.273

0.109

0.585

 

G/A

8.80 ± 9.50

 

A/A

7.44 ± 9.50

rs3805254

     
 

A/A

12.89 ± 12.14

0.273

0.109

0.585

 

A/G

8.80 ± 9.50

 

G/G

7.44 ± 9.50

  1. The values p < 0.05 were in bold
  2. a dominant model; b recessive model
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