Skip to main content

Table 1 Baseline characteristics of enrolled patients

From: Adjunct prednisone in community-acquired pneumonia: 180-day outcome of a multicentre, double-blind, randomized, placebo-controlled trial

 

Placebo (n = 366)

Prednisone (n = 361)

General characteristics

  

 Age, median (IQR), y

73 (61, 82)

74 (61, 84)

 Male Gender, No. (%)

231 (63.1%)

219 (60.7%)

Clinical variables

  

 Days with symptoms, median (IQR), d

4 (2, 7)

4 (2, 7)

 Temperature, median (IQR), °C

37.6 (37, 38.3)

37.5 (37, 38.2)

 Systolic blood pressure, median (IQR), mmHg

124 (110, 140)

124 (110, 140)

 Heart rate, median (IQR), bpm

82 (71, 96)

84 (74, 94)

 Respiratory Rate, median (IQR), bpm

20 (18, 24)

20 (18, 24)

 SaO2, median (IQR), %

94 (92, 96)

94.5 (92, 96)

 Confusion, No. (%)

27 (7.4%)

21 (5.8%)

Laboratory values

  

 Procalcitonin, median (IQR), ng/mL

0.43 (0.17, 2.3)

0.46 (0.17, 2.53)

 C-reactive protein, median (IQR), mg/L

159 (73.8, 249)

156 (80, 245.5)

 Leukocytes, median (IQR), × 109/L

11.98 (8.78, 15.6)

12.1 (8.88, 15.5)

Microbiological data

  

 Bacteraemia, No. (%)

45 (12.3%)

37 (10.2%)

 Bacterial etiology confirmed

87 (23.8%)

81 (22.4%)

 Viral etiology confirmed

38 (17.4%)

38 (17.8%)

PSI scorea

  

 PSI class I, No. (%)

41 (11.2%)

44 (12.2%)

 PSI class II, No. (%)

66 (18.0%)

66 (18.3%)

 PSI class III, No. (%)

86 (23.5%)

64 (17.7%)

 PSI class IV, No. (%)

125 (34.2%)

137 (38.0%)

 PSI class V, No. (%)

48 (13.1%)

50 (13.9%)

 Total PSI score, median (IQR),points

86 (65, 110)

93 (63, 115)

Comorbidities

  

 Diabetes mellitus, No. (%)

72 (19.7%)

66 (18.3%)

 Insulin treatment, No. (%)

23 (32%)

23 (35%)

 Chronic obstructive pulmonary disease, No. (%)

54 (14.8%)

70 (19.4%)

 Heart failure, No. (%)

58 (15.9%)

74 (20.5%)

 Cerebrovascular disease, No. (%)

30 (8.2%)

33 (9.1%)

 Renal insufficiency, No. (%)

117 (32.1%)

116 (32.1%)

 Neoplasia, No. (%)

22 (6.0%)

27 (7.5%)

 Liver disease, No. (%)

11 (3.0%)

17 (4.7%)

 Antibiotic pretreatment, No. (%)

89 (24.3%)

76 (21.1%)

  1. Data are median (IQR) or number (%), unless otherwise stated. SaO2 saturation of oxygen. PSI pneumonia severity index
  2. aThe PSI is a clinical prediction rule to calculate the probability of morbidity and mortality in patients with community-acquired pneumonia; PSI risk class I corresponds to age ≤ 50 years, and no risk factors (≤50 points), risk class II to < 70 points, risk class III to 71–90 points, risk class IV to 91–130 points, and risk class V to > 130 points [20]
Back to article page

BMC Pulmonary Medicine

ISSN: 1471-2466

Contact us