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Fig. 1 | BMC Pulmonary Medicine

Fig. 1

From: Whole-exome sequencing explored mechanism of selpercatinib resistance in RET-rearranged lung adenocarcinoma transformation into small-cell lung cancer: a case report

Fig. 1

Hematoxylin and eosin (HE) and immunohistochemical (IHC) staining at initial diagnosis. (A) The HE staining results were in accordance with the morphological characteristics typically observed in adenocarcinoma. (B) The cervical lymph node biopsy immunohistochemistry showed TTF-1 (+), CK (+), CK7(+), which was diagnosed as lung adenocarcinoma, and TG (-) excluded thyroid cancer. P53 mutated, RB1 deletion and Ki-67 expression was 30%. (C) Neuroendocrine markers as CD56, CgA and Syn were all negative at initial diagnosis

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BMC Pulmonary Medicine

ISSN: 1471-2466

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