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Fig. 3 | BMC Pulmonary Medicine

Fig. 3

From: Whole-exome sequencing explored mechanism of selpercatinib resistance in RET-rearranged lung adenocarcinoma transformation into small-cell lung cancer: a case report

Fig. 3

HE and IHC staining after liver metastasis. (A) HE staining showed that the cancer cells were small, the nuclei were dense and round or oval. (B) Adenocarcinoma marker NapsinA was negative, while neuroendocrine markers CD56, Syn and CgA were positive. P53 was mutant, RB1 was negative and Ki-67 expression was 80%

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