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Table 1 Gene fusions at initial diagnosis and after transformation

From: Whole-exome sequencing explored mechanism of selpercatinib resistance in RET-rearranged lung adenocarcinoma transformation into small-cell lung cancer: a case report

Initial diagnosis

(Adenocarcinoma)

After transformation

(SCLC)

Chromosome

Genetic fusion

Reads/VAF

Chromosome

Genetic fusion

Reads/VAF

Chr10

KIF5B》RET

0.3922

Chr10

KIF5B》RET

0.3965