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Table 4 Bivariate and Multivariate risk factor association with genotypic patterns of M. tuberculosis strain isolates

From: Strain structure analysis of Mycobacterium tuberculosis circulating among HIV negative, positive and drug resistant TB patients attending chest clinics in Western Kenya

Variable

Status

TOTAL

Genotypic pattern

Bivariate Analysis

Multivariate Analysis

Unique

Clustered

Unadjusted

Adjusted

OR

CI(95%)

P-Value

OR

CI (95%)

P-Value

Age

18–24

145 (26.22)

14(2.53)

131(23.69)

Ref

     

25–30

183(33.09)

23(4.15)

160(28.93)

0.95

0.35–2.27

0.003**

0.63

0.26–2.32

0.056

31–36

107(19.35)

17(3.07)

90(16.27)

2.13

0.96–6.12

0.81

1.67

0.33–3.23

0.72

37–42

47(8.50)

3(0.54)

44(7.96)

1.93

041–4.61

0.94

0.72

0.21–1.89

0.65

43–48

35(6.32)

3(0.54)

32(5.79)

2.16

0.98–6.78

0.31

1.53

0.43–2.87

1.45

49–54

18(3.25)

4(0.72)

14(2.53)

1.34

0.35–3.72

0.13

1.21

0.27–2.67

1.20

55–60

1(0.18)

1(0.18)

11(1.99)

0.85

0.23–3.10

0.12

0.45

0.12–2.98

0.35

61+

6(1.08)

0(0.00)

6(1.08)

1.23

0.16–3.81

0.48

0.94

0.43–2.78

0.87

HIV status

Positive

267(48.28)

26(4.70)

241(43.58)

1.73

0.42–5.21

0.04**

1.52

0.29–3.68

0.001**

Negative

286(51.71)

17(3.07)

269(48.64)

Ref

     

Sex

Female

208(37.61)

13(2.35)

195(35.26)

1.67

0.23–3.02

0.27

1.32

0.23–3.78

0.97

Male

345(62.38)

17(3.07)

326(58.95)

Ref

     

Education

No formal

144(26.04)

18(3.25)

126(22.78)

2.61

0.87–5.92

0.92

2.21

0.49–3.98

1.34

Primary

243(43.94)

14(2.53)

229(41.41)

Ref

     

Secondary

127(22.97)

19(3.43)

108(19.52)

2.32

0.61–5.24

0.71

2.13

0.49–3.09

1.98

Tertiary

39(7.05)

4(0.72)

35(6.32)

3.61

1.02–7.31

0.21

3.32

0.67–5.76

2.34

Occupation

Employed

83(15.01)

15(2.71)

68(2.30)

1.67

0.24–3.06

0.36

1.43

0.45–2.97

1.23

Self employed

218(39.42)

15(2.71)

203(36.71)

Ref

Ref

    

Informal employment

128(23.15)

21(3.80)

107(19.35)

1.52

0.21–2.98

0.54

1.22

0.22–3.21

0.98

Unemployed

103(18.62)

13(2.35)

90(16.27)

1.43

0.19–2.2.61

0.25

1.31

0.57–2.61

1.13

Student

10(1.81)

2(0.36)

8(1.45)

0.98

0.37–3.12

0.46

0.69

0.22–2.22

0.34

Other

11(1.99)

1(0.18)

10(1.80)

1.73

0.31–2.98

0.41

1.57

0.23–2.01

0.87

Monthly income

Less than Ksh. 1000

105(18.98)

10(1.80)

95(17.18)

Ref

     

Ksh. 1000–9, 999

160(28.93)

11(1.99)

149(26.94)

1.28

0.63–4.00

0.046**

1.19

0.27–3.02

0.52

Ksh. 10, 000–19, 999

174(31.46)

17(3.07)

157(28.75)

1.73

0.58–4.32

0.82

1.53

0.21–2.56

0.98

Ksh. 20,000–29, 999

48(8.68)

4(0.72)

44(7.96)

1.82

0.69–3.92

0.76

1.67

0.36–2.63

1.98

Ksh. 30,000-39,999

34(6.15)

2(0.36)

32(5.79)

1.23

0.42–3.62

0.34

0.98

0.32–3.21

0.71

Ksh. 40,000-49,999

18(3.25)

1(0.18)

17(3.07)

1.68

0.41–4.31

0.36

1.42

0.51–2.21

1.34

Ksh. 50,000 +

14(2.53)

2(0.36)

12(2.17)

1.53

0.29–3.93

0.54

1.37

0.31–2.87

1.43

Size of the house

Single room

122(22.06)

17(3.07)

105(18.99)

1.43

0.46–4.31

0.049**

1.27

0.29–3.02

0.056

Bedsitter

11(1.99)

3(0.54)

8(1.45)

1.83

0.32–3.61

0.71

1.59

0.36–3.42

0.78

One bedroom

207(37.43)

21(3.80)

186(33.63)

Ref

     

Two bedroom

191(34.54)

18(3.25)

173(31.28)

1.92

0.67–5.42

0.83

1.63

0.41–3.67

0.73

Other

22(3.98)

2(0.36)

20(3.62)

1.86

0.20–5.31

0.47

1.53

0.37–3.45

0.56

Cigarate smocking

Yes

132(23.87)

7(1.26)

125(22.6)

1.81

0.43–4.82

0.41

1.51

0.46–3.32

1.21

No

421(76.13)

14(2.53)

407(73.60)

Ref

     

Alcohol use

Yes

151(27.31)

16(2.89)

135(24.41)

0.87

0.34–5.34

0.003**

0.59

0.43–3.12

0.001**

No

402(72.69)

11(1.99)

391(70.70)

Ref

     

Cross boarder travels

Yes

211(38.15)

16(2.89)

195(35.26)

0.93

0.46–3.92

0.002**

0.61

0.49–3.87

0.026**

No

342(61.84)

17(3.07)

325(58.77)

Ref

     
  1. **P-value of <0.05 was considered significant. CI Confidence interval