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Table 1 Patient demographics and pulmonary function of patients

From: Safety and efficacy of cryobiopsy for the diagnosis of lymphangioleiomyomatosis compared with forceps biopsy and surgical lung biopsy

 

TBFB+

(n = 70)

count (%)

median (range)

TBCB+

(n = 20)

count (%)

median (range)

SLB+

(n = 45)

count (%)

median (range)

p value

 

All

TBFB+

vs.

TBCB+

TBFB+

vs.

SLB+

TBCB+

vs.

SLB+

Gender

       

 Female

70 (100%)

20 (100%)

45 (100%)

    

Age

38 (20,60)

36 (25,54)

36 (18,61)

0.713

   

PaO2(Torr)

96 (84,99)

(n = 56)

97 (86,99)

(n = 20)

97 (88,100)

(n = 35)

0.312

   

Smoking history

   

0.800

   

 Never

68 (97.1%)

20 (100%)

42 (97.7%)

    

 Current or ex-smoker

2 (2.9%)

0 (0%)

1 (2.3%)

    

Past history of pneumothorax

   

0.001

0.123

0.003

< 0.001

 Yes

27 (38.6%)

4 (20.0%)

29 (67.4%)

    

 No

43 (61.4%)

16 (80.0%)

14 (32.6%)

    

Chylous effusions

4 (5.7%)

0 (0.0%)

4 (5.7%)

0.202

   

Tuberous sclerosis complex

3 (4.3%)

2 (10.0%)

2 (4.7%)

0.639

   

Renal angiomyolipoma

10 (14.3%)

7 (35.0%)

6 (14.0%)

0.109

   

Number of specimens

5.5 (4,10)

n = 20

4 (3,5)

n = 12

  

0.016

  

%predicted DLco

42.50 (18.00,119.00)

n = 54

50.00 (24.00.94.80)

n = 19

56.00 (12.00,97.00)

n = 25

0.384

   

%predicted FEV1

58.00 (14.50,105.10)

n = 55

77.00 (23.60,138.70)

n = 20

62.00 (18.00,99.60)

n = 31

0.259

   

FEV1/FVC

58.52 (21.03,99.61)

n = 55

70.40 (22.74,87.10)

n = 20

76.62 (36.80,98.68)

n = 31

0.030

0.740

0.030

0.360

%predicted TLC

101.50 (64.00,138.90)

n = 50

105.00 (84.00,142.50)

n = 19

89.15 (59.10,124.80)

n = 22

0.013

0.999

0.036

0.020

%predicted RV

125.05 (67.00,326.20)

n = 50

127.00 (58.00,257.80)

n = 19

117.00 (74.00,254.00)

n = 22

0.736

   

RV/TLC

39.60 (22.58,77.18)

n = 50

38.80 (17.50,65.57)

n = 19

39.95 (28.80,68.88)

n = 22

0.634

   
  1. TBFB transbronchial lung forceps biopsy, TBCB transbronchial lung cryobiopsy, SLB surgical lung biopsy, + positive, − negative, PaO2 partial pressure of arterial oxygen, DLCO diffusing capacity of carbon monoxide, FEV1 forced expiratory volume in 1 s, FVC forced vital capacity, RV residual volume, TLC total lung capacity