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Fig. 5 | BMC Pulmonary Medicine

Fig. 5

From: Long non-coding RNA SNHG4 aggravates cigarette smoke-induced COPD by regulating miR-144-3p/EZH2 axis

Fig. 5

Verification of the interaction between miR-144-3p and EZH2. (A) Downstream target genes of miR-144-3p predicted by EVmiRNA and other databases. (B) Binding site of miR-144-3p and EZH2. (C) Luciferase reporter analysis. (D) The expression level of EZH2 in the serum of all the subjects. (E) The effect of miR-144-3p overexpression on EZH2 in Beas-2B cells. (F) Correlation between the expression of miR-144-3p and the expression of EZH2 in patients’ serum. ***P < 0.001, ###P < 0.001, &&&P < 0.001

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