Table 1 Comparison of baseline characteristics between COPD patients and healthy controls
From: Long non-coding RNA SNHG4 aggravates cigarette smoke-induced COPD by regulating miR-144-3p/EZH2 axis
Items | Control group (n = 60) | Stable COPD (n = 50) | Acute COPD (n = 50) | P |
|---|---|---|---|---|
Age (years) | 65.93 ± 5.72 | 66.29 ± 5.23 | 66.12 ± 5.65 | 0.247 |
Gender (male/female) | 46/14 | 38/12 | 37/13 | 0.616 |
BMI (kg/m2) | 22.89 ± 2.16 | 23.07 ± 1.98 | 22.75 ± 2.08 | 0.136 |
FEV1/FVC (%) | 91.55 ± 3.01 | 61.28 ± 6.16 | 53.37 ± 4.15 | < 0.001 |
FEV1 (predicted, %) | 96.72 ± 3.24 | 69.79 ± 12.93 | 51.56 ± 14.33 | < 0.001 |
Smoking history (n, %) | 17 (28.33%) | 24 (48.00%) | 31 (62.00%) | 0.009 |
IL-1β (pg/mL) | 30.12 ± 11.38 | 58.74 ± 9.08 | 77.52 ± 8.46 | < 0.001 |
IL-6 (pg/mL) | 101.54 ± 41.77 | 149.33 ± 32.07 | 199.83 ± 37.84 | < 0.001 |
TNF-α (pg/mL) | 82.34 ± 25.83 | 140.26 ± 45.75 | 202.23 ± 60.15 | < 0.001 |