Table 1 Characteristics in the study about patients with NRDS
Characteristics | Total cohort | Training cohort | Validation cohort | p |
|---|---|---|---|---|
Population | 2705 | 1899 | 806 | Â |
NRF population | 1194 (44.1%) | 838 (44.1%) | 356 (44.2%) | Â |
Gender (Male) (%) | 1558 (57.6) | 1098 (57.8) | 460 (57.1) | 0.751 |
Gestational age < 28 weeks (%) | 382 (26.8) | 267(27.1) | 115 (26.1) | 0.433 |
Ethnicity (%) | 0.12 | |||
 Asian | 184 (6.8) | 136 (7.2) | 48 (6.0) |  |
 Black | 312 (11.5) | 231 (12.2) | 81 (10.0) |  |
 White | 831 (30.7) | 581 (30.6) | 250 (31.0) |  |
 Other | 1378 (50.9) | 951 (50.1) | 427 (53.0) |  |
pH (median [IQR]) | 7.29 [7.23, 7.34] | 7.29 [7.24, 7.34] | 7.29 [7.23, 7.34] | 0.537 |
PCO2 (mmHg) (median [IQR]) | 51.00[44.00, 60.00] | 51.00 [44.00, 60.00] | 51.00 [43.00, 60.00] | 0.991 |
PO2 (mmHg) (median [IQR]) | 47.00[39.00, 58.00] | 47.00 [39.00, 58.00] | 47.00 [39.00, 58.00] | 0.895 |
WBC (× 109 /L) (median [IQR]) | 10.30 [6.97, 14.93] | 10.30[7.00,15.20] | 10.40[6.90,14.40] | 0.471 |
Hb (g/dL) (median [IQR]) | 15.80 [14.40, 17.30] | 15.90 [14.40, 17.30] | 15.80 [14.40, 17.38] | 0.961 |
PLT (× 109 /L) (median [IQR]) | 248.00 [201.00, 299.00] | 247.00 [200.00, 300.00] | 250.00 [202.00, 297.00] | 0.417 |
Bilirubin (mg/dL) (median [IQR]) | 5.50 [4.10, 7.80] | 5.50 [4.10, 7.75] | 5.50 [4.00, 8.10] | 0.602 |
Blood culture (%) | 0.412 | |||
 Not examined | 130 (4.8) | 103 (5.4) | 27 (3.3) |  |
 Negative | 2428 (89.8) | 1688 (88.9) | 740 (91.8) |  |
 Positive | 147 (5.4) | 108 (5.7) | 39 (4.8) |  |
CSF culture (%) | 0.468 | |||
 Not examined | 2399 (88.7) | 1687 (88.8) | 712 (88.3) |  |
 Negative | 295 (10.9) | 206 (10.8) | 89 (11.0) |  |
 Positive | 11 (0.4) | 6 (0.3) | 5 (0.6) |  |
Disease time (median [IQR]) | 3.96 [0.13, 22.39] | 3.98 [0.13, 22.73] | 3.96 [0.13, 21.31] | 0.576 |
Infection (%) | 446 (16.5) | 305 (16.1) | 141 (17.5) | 0.389 |
IUGR (%) | 214 (7.8) | 156 (8.1) | 58 (7.0) | 0.378 |
Neonatal anemia (%) | 818 (29.8) | 579 (30.1) | 239 (29.0) | 0.599 |
Neonatal apnea (%) | 1735 (63.1) | 1204 (62.6) | 531 (64.4) | 0.376 |
Neonatal asphyxia (%) | 8 (0.3) | 7 (0.4) | 1 (0.1) | 0.487 |
Neonatal coagulation disorders (%) | 119 (4.3) | 87 (4.5) | 32 (3.9) | 0.515 |
Neonatal intracranial Hemorrhage (%) | 119 (4.3) | 87 (4.5) | 32 (3.9) | 0.515 |
Neonatal pneumonia (%) | 43 (1.6) | 31 (1.6) | 12 (1.5) | 0.895 |
Caffeine (%) | 1185 (43.1) | 827 (43.0) | 358 (43.4) | 0.855 |
PS (%) | 1006 (36.6) | 705 (36.6) | 301 (36.5) | 0.989 |
Parenteral nutrition (%) | 1339 (48.7) | 932 (48.4) | 407 (49.4) | 0.677 |
Respiratory support (%) | 1850 (68.4) | 1313 (69.1) | 537 (66.6) | 0.214 |