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Fig. 2 | BMC Pulmonary Medicine

Fig. 2

From: Association of serum vitamin C levels with Asthma in adults: results of NHANES 2003–2006 and mendelian randomization study

Fig. 2

Mendelian randomization model and study overview. Red cross indicates that this pathway cannot be allowed. Assumption (1): There is a strong correlation between SNPs and exposure; Assumption (2): SNPs and confounders are independent of each other; Assumption (3): SNPs can only contribute to outcome through exposure. SNPs, single nucleotide polymorphisms; GWAS, genome wide association study; IVW, inverse-variance weighted; MR-PRESSO, Mendelian Randomization Pleiotropy RESidual Sum and Outlier

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