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Table 4 Factors associated with the incidence rate of mild exacerbation* in bronchiectasis patients

From: Understanding the effects of Haemophilus influenzae colonization on bronchiectasis: a retrospective cohort study

Variables

Unadjusted IRR

P

Adjusted IRR

P

H. influenzae colonization

1.63 [1.08–2.44]

0.019

1.54 [1.06–2.24]

0.023

P. aeruginosa colonization

2.04 [1.38–3.03]

< 0.001

1.70 [1.12–2.56]

0.012

Bacteria other than H. influenzae and P. aeruginosa colonization

1.90 [1.27–2.84]

0.002

1.31 [0.86–1.99]

0.208

BMI (kg/m2)

0.93 [0.88–0.99]

0.023

0.96 [0.91–1.02]

0.190

Chronic obstructive pulmonary disease

1.85 [1.18–2.91]

0.008

1.03 [0.67–1.58]

0.896

Asthma

1.71 [1.02–2.86]

0.041

1.77 [1.10–2.85]

0.019

Hospitalization history within two years

2.25 [1.22–4.14]

0.009

1.52 [0.86–2.66]

0.148

Involvement ≥ 3 lobes

2.50 [1.69–3.68]

< 0.001

1.72 [1.14–2.57]

0.009

  1. *Mild exacerbation refers to an outpatient prescription of oral antibiotics due to exacerbation. Colonization was defined as when any type of bacteria was detected at least once from respiratory specimen culture during routine practice. Data are shown as median [interquartile range] unless specified otherwise. Abbreviations: IRR, incidence rate ratio; BMI, Body Mass Index
  2. Abbreviations: ICD, International Classification of Diseases; CT, computed tomography; NTM-PD, Non-tuberculous mycobacterial pulmonary disease