Table 1 Demographic and clinical characteristics in SCLC patients with liver metastasis
Variables | Total (n = 8,587) | Training set (n = 6,440) | Testing set (n = 2,147) |
|---|---|---|---|
Age, n (%), years | |||
≤ 65 | 3770 (43.90) | 2796 (43.42) | 974 (45.37) |
> 65 | 4817 (56.10) | 3644 (56.58) | 1173 (54.63) |
Gender, n (%) | |||
Female | 3988 (46.44) | 2947 (45.76) | 1041 (48.49) |
Male | 4599 (53.56) | 3493 (54.24) | 1106 (51.51) |
Race, n (%) | |||
Black | 663 (7.72) | 491 (7.62) | 172 (8.01) |
White | 7629 (88.84) | 5731 (88.99) | 1898 (88.40) |
Others | 295 (3.44) | 218 (3.39) | 77 (3.59) |
Marital status, n (%) | |||
Other | 4300 (50.08) | 3223 (50.05) | 1077 (50.16) |
Married | 4287 (49.92) | 3217 (49.95) | 1070 (49.84) |
Primary sites, n (%) | |||
Multiple | 134 (1.56) | 95 (1.48) | 39 (1.82) |
Upper lobe | 3698 (43.07) | 2797 (43.43) | 901 (41.97) |
Middle lobe | 262 (3.05) | 205 (3.18) | 57 (2.65) |
Lower lobe | 1753 (20.41) | 1309 (20.33) | 444 (20.68) |
Main bronchus | 937 (10.91) | 701 (10.89) | 236 (10.99) |
NOS | 1803 (21.00) | 1333 (20.70) | 470 (21.89) |
Tumor sizes, n (%) | |||
0–24 mm | 2036 (23.71) | 1527 (23.71) | 509 (23.71) |
25–37 mm | 2193 (25.54) | 1648 (25.59) | 545 (25.38) |
38–59 mm | 2184 (25.43) | 1634 (25.37) | 550 (25.62) |
≥ 60 mm | 2174 (25.32) | 1631 (25.32) | 543 (25.29) |
T stage, n (%) | |||
T0 | 105 (1.22) | 77 (1.20) | 28 (1.30) |
T1 | 640 (7.45) | 471 (7.31) | 169 (7.87) |
T2 | 1835 (21.37) | 1393 (21.63) | 442 (20.59) |
T3 | 1603 (18.67) | 1180 (18.32) | 423 (19.70) |
T4 | 2870 (33.42) | 2165 (33.62) | 705 (32.84) |
Tx | 1534 (17.86) | 1154 (17.92) | 380 (17.70) |
N stage, n (%) | |||
N0 | 890 (10.36) | 678 (10.53) | 212 (9.87) |
N1 | 519 (6.04) | 5.82 (16.35) | 144 (6.71) |
N2 | 4779 (55.65) | 3564 (55.34) | 1215 (56.59) |
N3 | 1849 (21.53) | 1399 (21.72) | 450 (20.96) |
Nx | 550 (6.41) | 424 (6.58) | 126 (5.87) |
Metastatic lesion, n (%) | |||
Bone | 2153 (25.07) | 1599 (24.83) | 554 (25.80) |
Brain | 565 (6.58) | 419 (6.51) | 146 (6.80) |
Lung | 729 (8.49) | 537 (8.34) | 192 (8.94) |
Multiple metastases | 1527 (17.78) | 1147 (17.81) | 380 (17.70) |
No or unknown | 3613 (42.08) | 2738 (42.52) | 875 (40.75) |
Surgery of primary site, n (%) | |||
No/unknown | 8553 (99.60) | 6414 (99.60) | 2139 (99.63) |
Yes | 34 (0.40) | 26 (0.40) | 8 (0.37) |
Surgery of metastatic site, n (%) | |||
Not/unknown | 8416 (98.01) | 6309 (97.97) | 2107 (98.14) |
Yes | 171 (1.99) | 131 (2.03) | 40 (1.86) |
Chemotherapy, n (%) | |||
Not/unknown | 3059 (35.62) | 2292 (35.59) | 767 (35.72) |
Yes | 5528 (64.38) | 4148 (64.41) | 1380 (64.28) |
Radiotherapy, n (%) | |||
Not/unknown | 6216 (72.39) | 4664 (72.42) | 1552 (72.29) |
Yes | 2371 (27.61) | 1776 (27.58) | 595 (27.71) |
CSS | 0.0179 | 0.0174 | 0.0196 |
OS | 1.79% | 1.74% | 1.96% |