Table 5 The results among lung cancer types detected by NGS
From: Genomic features of lung cancer patients in Indonesia’s national cancer center
Result | n (%) | |||||
|---|---|---|---|---|---|---|
Adenocarcinoma | SCC | Other NSCLC | SCLC | p-value | ||
Single gene variant | EGFR | 42 (53.2%) | 1 (100%) | 0 | 0 | 0.000 |
TP53 | 5 (6.2%) | 0 | 0 | 0 | ||
KRAS | 1 (1.3%) | 0 | 0 | 0 | ||
PIK3CA | 1 (1.3%) | 0 | 0 | 0 | ||
Co-variant | EGFR/TP53 | 11 (13.9%) | 0 | 0 | 0 | 0.000 |
EGFR/TP53/KRAS | 1 (1.3%) | 0 | 0 | 0 | ||
EGFR/TP53/KRAS/PIK3CA | 1 (1.3%) | 0 | 0 | 0 | ||
EGFR/KRAS | 1 (1.3%) | 0 | 0 | 0 | ||
EGFR/KRAS/BRAF | 1 (1.3%) | 0 | 0 | 0 | ||
EGFR/MET | 2 (2.4%) | 0 | 0 | 0 | ||
EGFR/PIK3CA | 7 (8.9%) | 0 | 0 | 0 | ||
EGFR/PIK3CA/MAP2K1 | 1 (1.3%) | 0 | 0 | 0 | ||
EGFR/ROS1 | 1 (1.3%) | 0 | 0 | 0 | ||
KRAS/TP53 | 1 (1.3%) | 0 | 0 | 0 | ||
NRAS/TP53 | 1 (1.3%) | 0 | 0 | 0 | ||
Wild type | 2 (2.4%) | 0 | 0 | 0 | 0.000 | |
Total | 79 | 1 | 0 | 0 | ||