Table 1 Baseline characteristics of elderly SCAP‡ individuals in training cohort and testing cohort
Variables | Overall (n = 2365) | training cohort (n = 1655) | testing cohort (n = 710) | P†-value | |
|---|---|---|---|---|---|
Demographic characteristics | |||||
Age (years old) | 74 (69, 80) | 75 (69, 81) | 74 (69, 80) | 0.871 | |
Male, n (%) | 1529 (64.7) | 1067 (64.5) | 462 (65.1) | 0.780 | |
Prognosis | |||||
7-day mortality, n (%) | 152 (6.4) | 103 (6.2) | 49 (6.9) | 0.538 | |
14-day mortality, n (%) | 311 (13.2) | 213 (12.9) | 98 (13.8) | 0.538 | |
28-day mortality, n (%) | 621 (26.3) | 426 (25.7) | 195 (27.5) | 0.382 | |
ICU mortality, n (%) | 755 (31.9) | 519 (31.4) | 236 (33.2) | 0.368 | |
In-hospital mortality, n (%) | 868 (36.7) | 600 (36.3) | 268 (37.7) | 0.490 | |
Length of stay in hospital(d) | 21 (12, 31) | 21 (12, 31) | 20 (12, 31) | 0.788 | |
Treatment | |||||
Vasopressor, n (%) | 1432 (60.5) | 993 (60.0) | 439 (61.8) | 0.404 | |
Comorbidities | |||||
Cancer, n (%) | 428 (18.1) | 312 (18.9) | 116 (16.3) | 0.146 | |
Diabetes mellitus, n (%) | 392 (16.6) | 271 (16.4) | 121 (17.0) | 0.689 | |
Chronic hepatic diseases (%) | 65 (2.7) | 43 (2.6) | 22 (3.1) | 0.495 | |
Chronic renal diseases (%) | 175 (7.4) | 130 (7.9) | 45 (6.3) | 0.196 | |
Chronic cardiac diseases (%) | 995 (42.1) | 717 (18.5) | 278 (39.2) | 0.060 | |
Vital signs on admission | |||||
Respiratory rate(times/min) | 19 (14, 23) | 19 (14, 24) | 18 (14, 23) | 0.240 | |
Heart rate (beat/min) | 95.47 (94.51–96.43) | 95.8 (94.75–97.03) | 94.49 (92.71–96.27) | 0.213 | |
Systolic blood pressure (mmHg) | 128.72 (127.38-130.06) | 128.62 (126.96-130.18) | 129.08 (126.65–131.50) | 0.734 | |
Diastolic blood pressure (mmHg) | 69.89 (69.10-70.68) | 69.88 (68.93–70.83) | 69.90 (68.47–71.34) | 0.918 | |
Laboratory examinations | |||||
White blood cell (× 109/L) | 9.75 (6.58, 13.37) | 9.53 (6.52, 13.36) | 9.70 (6.75, 13.39) | 0.3664 | |
Monocyte (× 109/L) | 0.43 (0.27, 0.62) | 0.42 (0.27, 0.62) | 0.43 (0.27, 0.62) | 0.940 | |
Neutrophil (× 109/L) | 7.87 (4.91, 11.53) | 7.77 (4.88, 11.50) | 8.23 (5.01, 11.82) | 0.175 | |
Lymphocyte (× 109/L) | 0.83 (0.53, 1.24) | 0.83 (0.53, 1.24) | 0.81 (0.53, 1.21) | 0.307 | |
Platelet (× 109/L) | 165 (106, 237) | 165 (104, 240) | 166 (110, 236) | 0.699 | |
Hemoglobin (g/L) | 107.95 (106.92-108.98) | 107.67 (106.42-108.92) | 108.60 (106.76-110.43) | 0.441 | |
Total bilirubin (µmol/L) | 11.2 (7.8, 16.6) | 11.0 (7.7, 16.1) | 11.6 (8.1, 17.6) | 0.057 | |
Direct bilirubin (µmol/L) | 5.3 (3.5, 8.4) | 5.1 (3.5, 8.1) | 5.4 (3.5, 8.8) | 0.031 | |
Albumin (g/L) | 32.82 (32.56–33.07) | 32.84 (32.53–33.15) | 32.76 (32.30-33.23) | 0.741 | |
Globulin (g/L) | 25.71 (25.46–25.95) | 25.76 (25.46–26.06) | 25.58 (25.14–26.01) | 0.535 | |
ALT‡ (IU/L) | 20 (12, 37) | 19 (12, 36) | 20 (13, 38) | 0.161 | |
AST‡ (IU/L) | 27 (19, 47) | 27 (19, 46) | 29 (20, 51) | 0.068 | |
Creatinine (µmol/L) | 75.00 (56.35, 109.00) | 75.00 (57.00, 108.15) | 75.00 (55.25, 112.00) | 0.600 | |
BUN‡ (mg/dL) | 7.63 (5.36, 12.30) | 7.53 (5.40, 12.40) | 7.81 (5.21, 12.13) | 0.693 | |
Lactate (mmol/L) | 1.5 (1.1, 2.0) | 1.5 (1.1, 2.0) | 1.5 (1.1, 2.1) | 0.384 | |
Uric acid (µmol/L) | 243.0 (152.9, 346.6) | 247.5 (152.3, 349.0) | 235.0 (153.8, 337.0) | 0.413 | |
Glucose (mmol/L) | 7.12 (5.88, 9.59) | 7.13 (5.90, 9.58) | 7.09 (5.71, 9.60) | 0.640 | |
APTT‡ (s) | 32.3 (27.9, 38.9) | 32.3 (28.0, 38.8) | 32.3 (27.9, 39.8) | 0.766 | |
PT‡ (s) | 12.9 (11.8, 14.4) | 12.9 (11.9, 14.4) | 12.8 (11.8, 14.5) | 0.688 | |
D-Dimer (mg/L) | 4.53 (2.23, 9.05) | 4.62 (2.28, 9.05) | 4.37 (2.13, 9.03) | 0.582 | |
Troponin T (ng/mL) | 27.90 (19.95, 68.80) | 27.45 (20.0, 65.9) | 28.80 (19.77, 75.05) | 0.301 | |
BNP‡ (pg/mL) | 1078 (553.5, 3939.5) | 1088 (564, 4046) | 1043 (536, 3790) | 0.573 | |
PCT‡ (ng/mL) | 0.33 (0.15, 1.10) | 0.33 (0.15, 1.08) | 0.33 (0.15, 1.12) | 0.195 | |
IL-6(pg/ml) | 47.83(27.70, 102.70) | 47.83 (27.61, 102.60) | 47.83 (27.82, 104.08) | 0.626 | |
CRP‡ (mg/L) | 63.45 (27.55, 105.00) | 63.45 (27.20, 104.00) | 63.45 (81.10) | 0.945 | |