Table 2 Risk factors associated with in-hospital mortality in training cohort

Age

1.049 (1.034, 1.063)

< 0.001

1.042 (1.025, 1.058)

< 0.001

The use of vasopressor

3.939 (3.127, 4.963)

< 0.001

3.748 (2.933, 4.789)

< 0.001

Comorbidities

 Chronic hepatic diseases

2.063 (1.123, 3.788)

0.020

 Chronic renal diseases

3.844 (2.633, 5.613)

< 0.001

3.309 (1.995, 4.631)

< 0.001

Vital signs

 Respiratory rate

1.029 (1.013, 1.045)

< 0.001

 Heart rate

1.009 (1.005, 1.013)

< 0.001

 Systolic blood pressure (mmHg)

0.996 (0.993, 0.999)

0.018

 Diastolic blood pressure (mmHg)

0.992 (0.987, 0.997)

0.003

 FiO₂

1.011 (1.006, 1.015)

< 0.001

Laboratory examinations

 Neutrophil (×109/L)

1.043 (1.024, 1.062)

< 0.001

1.021 (1.000, 1.042)

0.050

 Lymphocyte (×109/L)

0.789 (0.678, 0.917)

0.002

 Hemoglobin (g/L)

0.991 (0.987, 0.995)

< 0.001

 Platelet (×109/L)

0.997 (0.996, 0.998)

< 0.001

0.998 (0.997, 1.000)

0.005

 APTT ^‡ (s)

1.018 (1.010, 1.025)

< 0.001

 PT^‡ (s)

1.039 (1.019, 1.059)

< 0.001

 Albumin (g/L)

0.961 (0.946, 0.977)

< 0.001

 ALT^‡ (IU/L)

1.001 (1.000. 1.001)

0.022

 AST^‡ (IU/L)

1.001 (1.000, 1.001)

0.015

 Creatinine (µmol/L)

1.002 (1.001, 1.003)

< 0.001

 Uric acid (µmol/L)

1.001 (1.001, 1.002)

< 0.001

 Myoglobin (ng/mL)

1.000 (1.000, 1.001)

< 0.001

 BUN^‡ (mg/dL)

1.050 (1.036, 1.064)

< 0.001

1.032 (1.009, 1.055)

0.006

 Glucose (mmol/L)

1.045 (1.018, 1.074)

0.001

 CRP^‡ (mg/L)

1.002 (1.001, 1.004)

< 0.001

 Lactate (mmol/L)

1.104 (1.044, 1.167)

< 0.001

 PCT^‡ (ng/mL)

1.013 (1.003, 1.024)

0.009