Fig. 4
Effects of SOCS5 expression on HPASMC contractility under hypoxia conditions. A Representative image of cell contraction assay. The red circles represent the gel area. B Quantification of collagen contraction relative to the initial collagen gel area (n = 3 each group). C Representative images of [Ca2+]. Scale bar = 100 μm. D Quantitative analysis of Fluo-4 AM fluorescence intensity (n = 3 each group). Fluo-4 AM, a fluorescent dye. HPASMCs, human pulmonary arterial smooth muscle cells