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Table 1 Baseline demographics and clinical characteristics of enrolled patients

From: Value of preoperative evaluation of FEV1 in patients with destroyed lung undergoing pneumonectomy - a 20-year real-world study

Variables

Total

(n = 123, %)

FEV1 >2 L

(n = 30, %)

FEV1 ≤ 2 L

(n = 93, %)

P value

Sex, M

42(34.1)

18.0(60.0)

24.0(25.8)

0.001

Age group

40.1 ± 13.8

39.5 ± 14.3

40.2 ± 13.7

0.792

BMI, kg/m2

21.3 ± 3.1

21.0 ± 3.2

21.4 ± 3.1

0.527

Smoking history*

14(11.4)

7(23.3)

7(7.5)

0.027

Alcohol abuse

7(5.7)

3(10.0)

4(4.3)

0.360

Comorbidities

    

 Previous history of pulmonary tuberculosis

36(12,120)

42(9,120)

36(12,174)

0.354

 Other disease#

22(17.9)

6(20.0)

16(17.2)

0.728

 CPA

18(14.6)

3(10.0)

15(16.1)

0.392

 MDR/XDR

20(16.3)

7(23.3)

13(14.0)

0.242

Chronic pulmonary symptoms

    

 mMRC ≥ 1

70(56.9)

14(46.7)

56(60.2)

0.193

 Massive hemoptysis

20(16.3)

4(13.3)

16(17.2)

0.611

 Fever

18(14.6)

5(16.7)

13(14.0)

0.720

 Sputum

71(57.7)

17(56.7)

54(58.1)

0.893

Pulmonary function test

    

 FVC % pred

59.1 ± 12.8

65.1 ± 14.4

57.2 ± 11.6

0.003

 DLCO % pred

57.2 ± 19.2

54.3 ± 13.5

58.1 ± 20.7

0.336

Chest CT

    

 Cavity

37(30.1)

14(46.7)

23(24.7)

0.023

 Contralateral Pulmonary lesions

82(66.7)

20(66.7)

62(66.7)

1.000

Ancillary blood test

    

 HB, g/L

121.6 ± 15.4

125.9 ± 15.7

120.2 ± 15.2

0.079

 ALB, g/L

38.7 ± 5.7

40.0 ± 7.36

38.3 ± 5.1

0.161

 CRP, mg/L

8.4(2.2,29.0)

15.5(2.8,39.2)

7.4(2.0,22.2)

0.062

The operation factors

    

 Surgical removal of right

25(20.3)

5(16.7)

20(21.5)

0.567

 Time of operation, h

152(120,180)

150(120,185)

155(120,180.0)

0.739

 Mean bleeding volum, mL

700(300,1300)

800(475,2050)

600(300,1150)

0.180

  1. Note: *, Ex or current smoker; #, Other comorbidities including 2 cases of hepatitis B, 2 cases of Ankylosing Spondylitis, 1 cases of rheumatoid, 1 cases of gastric ulcer, 2 cases of hypertension and 6 cases of coronary heart disease; In view of small sample size of patients with comorbidities, they were combined into one group for statistical analysis
  2. Abbreviation: DL, destroyed lung; mMRC, Modified British Medical Research Council; BMI, body mass index; PFT, Pulmonary function test; CPA, chronic pulmonary aspergillosis; MDR/XDR, multidrug resistant tuberculosis/ extensively drug-resistant; HB, hemoglobin; ALB, albumin; CRP, C-reaction protein; FVC% pred, forced vital capacity of predicted value; FEV1 (% pred), forced expiratory volume in one second of predicted; MMV (% pred), maximal minute ventilation of predicted; DLCO (% pred), lung diffusion capacity of predicted