Table 4 Comparison of time to deterioration event in different Cpn IgA status
Time to deterioration event of Cpn IgAn(%) | χ2 | P | Time to deterioration of Cpn IgAM (P25, P75) | HR (95% CI) | P | |||
|---|---|---|---|---|---|---|---|---|
Cpn IgA − | Cpn IgA + | Cpn IgA − | Cpn IgA + | |||||
QLQ-C30 | ||||||||
Global health status (QL) | 30 (66.7) | 22 (59.5) | 0.455 | 0.500 | 14.59 (6.11, 27.14) | 26.87 (13.37, 30.06) | 0.678 (0.385–1.192) | 0.177 |
Functional scales | ||||||||
Physical functioning (PF) | 31 (68.9) | 18 (48.6) | 3.459 | 0.063 | 9.99 (4.57, 23.95) | 24.38 (14.55, 29.40) | 0.491 (0.270–0.894) | 0.020 |
Role functioning (RF) | 21 (46.7) | 12 (32.4) | 1.711 | 0.191 | 15.74 (4.67, 29.01) | 26.87 (14.78, 30.06) | 0.575 (0.275–1.201) | 0.141 |
Emotional functioning (EF) | 16 (35.6) | 10 (27.0) | 0.682 | 0.409 | 23.03 (9.99, 30.29) | 26.87 (14.78, 30.49) | 0.604 (0.267–1.370) | 0.228 |
Cognitive functioning (CF) | 17 (37.8) | 13 (35.1) | 0.061 | 0.805 | 23.95 (11.96, 30.29) | 26.25 (14.78, 29.73) | 0.779 (0.371–1.637) | 0.510 |
Social functioning (SF) | 11 (24.4) | 7 (18.9) | 0.111 | 0.739 | 24.05 (11.96, 31.11) | 28.02 (16.36, 30.49) | 0.658 (0.241–1.798) | 0.415 |
Symptom scales/items | ||||||||
Fatigue (FA) | 17 (37.8) | 10 (27.0) | 1.063 | 0.303 | 23.03 (6.60, 29.01) | 26.87 (14.55, 30.06) | 0.573 (0.254–1.292) | 0.179 |
Nausea and vomiting (NV) | 12 (26.7) | 9 (24.3) | 0.058 | 0.809 | 23.95 (12.94, 31.08) | 28.85 (16.36, 30.49) | 0.725 (0.296–1.778) | 0.482 |
Pain (PA) | 24 (53.3) | 15 (40.5) | 1.332 | 0.248 | 12.94 (5.19, 25.95) | 24.38 (13.31, 29.70) | 0.607 (0.313–1.178) | 0.140 |
Dyspnoea (DY) | 19 (42.2) | 10 (27.0) | 2.051 | 0.152 | 23.66 (6.60, 29.70) | 28.02 (16.07, 30.49) | 0.513 (0.231–1.142) | 0.102 |
Insomnia (SL) | 22 (48.9) | 16 (43.2) | 0.260 | 0.610 | 21.19 (7.66, 27.83) | 26.87 (14.78, 30.06) | 0.656 (0.338–1.274) | 0.213 |
Appetite loss (AP) | 15 (33.3) | 11 (29.7) | 0.122 | 0.727 | 23.95 (9.72, 30.29) | 28.85 (16.07, 30.49) | 0.726 (0.325–1.621) | 0.434 |
Constipation (CO) | 13 (28.9) | 8 (21.6) | 0.563 | 0.453 | 23.85 (9.99, 29.70) | 28.02 (14.78, 30.49) | 0.609 (0.241–1.539) | 0.294 |
Diarrhoea (DI) | 15 (33.3) | 7 (18.9) | 2.149 | 0.143 | 23.95 (12.94, 31.08) | 28.02 (16.07, 30.49) | 0.463 (0.178–1.203) | 0.114 |
Financial difficulties (FI) | 11 (24.4) | 8 (21.6) | 0.091 | 0.763 | 23.95 (8.44, 31.08) | 28.02 (16.36, 30.49) | 0.709 (0.274–1.833) | 0.478 |
QLQ-LC13 | ||||||||
Dyspnoea (LC-DY) | 26 (57.8) | 17 (45.9) | 1.140 | 0.286 | 12.94 (5.19, 25.95) | 25.07 (12.78, 29.40) | 0.593 (0.317–1.112) | 0.103 |
Coughing (LC-CO) | 18 (40.0) | 11 (29.7) | 0.937 | 0.333 | 18.79 (6.54, 29.01) | 28.02 (14.55, 30.49) | 0.543 (0.250–1.179) | 0.123 |
Haemoptysis (LC-HA) | 10 (22.2) | 7 (18.9) | 0.135 | 0.714 | 23.95 (12.94, 31.08) | 28.02 (16.07, 30.49) | 0.656 (0.238–1.807) | 0.414 |
Sore mouth (LC-SM) | 11 (24.4) | 6 (16.2) | 0.837 | 0.360 | 23.95 (12.94, 31.11) | 28.85 (16.36, 30.49) | 0.506 (0.175–1.466) | 0.210 |
Dysphagia (LC-DS) | 10 (22.2) | 8 (21.6) | 0.004 | 0.948 | 23.95 (12.94, 31.08) | 28.02 (16.36, 30.49) | 0.772 (0.293–2.033) | 0.600 |
Peripheral neuropathy (LC-PN) | 11 (24.4) | 10 (27.0) | 0.071 | 0.790 | 23.95 (12.94, 31.08) | 26.25 (14.78, 30.06) | 0.951 (0.394–2.296) | 0.911 |
Alopecia (LC-HR) | 16 (35.6) | 9 (24.3) | 1.209 | 0.272 | 23.66 (10.28, 29.01) | 26.87 (16.07, 30.06) | 0.546 (0.232–1.285) | 0.166 |
Pain in chest (LC-PC) | 20 (44.4) | 11 (29.7) | 1.870 | 0.172 | 15.74 (7.66, 27.14) | 25.95 (14.55, 29.73) | 0.479 (0.224–1.026) | 0.058 |
Pain in aim or should (LC-PA) | 17 (37.8) | 11 (29.7) | 0.585 | 0.444 | 23.85 (8.67, 29.70) | 25.95 (14.78, 29.73) | 0.828 (0.379–1.812) | 0.637 |
Pain in other parts (LC-PO) | 19 (42.2) | 15 (40.5) | 0.024 | 0.878 | 22.93 (8.80, 28.48) | 26.25 (13.37, 29.73) | 0.781 (0.390–1.565) | 0.486 |