Table 5 Comparison of time to deterioration event in different Cpn IgG status
Time to deterioration event of Cpn IgGn(%) | χ2 | P | Time to deterioration of Cpn IgGM (P25, P75) | HR (95% CI) | P | |||
|---|---|---|---|---|---|---|---|---|
Cpn IgG − | Cpn IgG + | Cpn IgG − | Cpn IgG + | |||||
QLQ-C30 | ||||||||
Global health status (QL) | 13 (65.0) | 39 (62.9) | 0.029 | 0.866 | 21.44 (12.97, 30.05) | 17.41 (6.50, 29.63) | 1.242 (0.648–2.380) | 0.514 |
Functional scales | ||||||||
Physical functioning (PF) | 14 (70.0) | 35 (56.5) | 1.154 | 0.283 | 18.09 (6.27, 25.88) | 15.15 (5.19, 27.97) | 1.126 (0.579–2.190) | 0.726 |
Role functioning (RF) | 10 (50.0) | 23 (37.1) | 1.047 | 0.306 | 21.23 (11.36, 30.05) | 23.95 (5.20, 29.72) | 0.989 (0.454–2.153) | 0.977 |
Emotional functioning (EF) | 11 (55.0) | 15 (24.2) | 6.628 | 0.010 | 18.71 (11.36, 26.06) | 25.95 (13.45, 30.49) | 0.422 (0.189–0.941) | 0.035 |
Cognitive functioning (CF) | 10 (50.0) | 20 (32.3) | 2.052 | 0.152 | 23.76 (14.18, 30.05) | 25.63 (13.33, 29.98) | 0.701 (0.319–1.544) | 0.378 |
Social functioning (SF) | 7 (35.0) | 11 (17.7) | 1.718 | 0.190 | 24.02 (15.45, 31.79) | 26.56 (14.61, 30.49) | 0.632 (0.232–1.718) | 0.368 |
Symptom scales/items | ||||||||
Fatigue (FA) | 8 (40.0) | 19 (30.6) | 0.599 | 0.439 | 23.76 (12.94, 30.05) | 24.00 (8.61, 29.72) | 0.965 (0.405–2.302) | 0.937 |
Nausea and vomiting (NV) | 4 (20.0) | 17 (27.4) | 0.437 | 0.509 | 24.61 (18.03, 34.42) | 26.10 (14.61, 30.44) | 1.999 (0.585–6.829) | 0.269 |
Pain (PA) | 12 (60.0) | 27 (43.5) | 1.641 | 0.200 | 18.71 (8.93, 29.18) | 17.41 (5.44, 28.85) | 0.900 (0.443–1.831) | 0.771 |
Dyspnoea (DY) | 9 (45.0) | 20 (32.3) | 1.074 | 0.300 | 24.12 (14.18, 31.79) | 25.19 (10.06, 29.98) | 0.914 (0.400–2.088) | 0.831 |
Insomnia (SL) | 12 (60.0) | 26 (741.9) | 1.985 | 0.159 | 20.86 (8.94, 30.75) | 24.56 (10.41, 29.63) | 0.769 (0.378–1.565) | 0.469 |
Appetite loss (AP) | 7 (35.0) | 19 (30.6) | 0.132 | 0.716 | 24.02 (14.18, 31.79) | 25.95 (13.67, 30.44) | 1.077 (0.429–2.704) | 0.875 |
Constipation (CO) | 7 (35.0) | 14 (22.6) | 1.224 | 0.269 | 23.76 (14.18, 30.05) | 25.63 (13.33, 30.23) | 0.771 (0.296–2.010) | 0.595 |
Diarrhoea (DI) | 5 (25.0) | 17 (27.4) | 0.045 | 0.832 | 24.12 (15.45, 31.79) | 26.10 (13.67, 30.44) | 1.387 (0.466–4.128) | 0.557 |
Financial difficulties (FI) | 7 (35.0) | 12 (19.4) | 1.293 | 0.256 | 21.23 (11.36, 30.05) | 26.56 (14.61, 30.49) | 0.605 (0.227–1.613) | 0.315 |
QLQ-LC13 | ||||||||
Dyspnoea (LC-DY) | 13 (65.0) | 30 (48.4) | 1.673 | 0.196 | 15.79 (6,25, 29.18) | 20.75 (7.85, 28.85) | 0.865 (0.438–1.707) | 0.675 |
Coughing (LC-CO) | 8 (40.0) | 21 (33.9) | 0.249 | 0.618 | 24.02 (8.93, 32.30) | 24.00 (8.50, 29.72) | 0.965 (0.410–2.271) | 0.935 |
Haemoptysis (LC-HA) | 5 (25.0) | 12 (19.4) | 0.050 | 0.823 | 24.12 (15.45, 31.79) | 26.10 (13.67, 30.44) | 0.973 (0.313–3.019) | 0.962 |
Sore mouth (LC-SM) | 5 (25.0) | 12 (19.4) | 0.050 | 0.823 | 24.61 (18.03, 34.42) | 26.10 (14.61, 30.49) | 1.086 (0.349–3.383) | 0.887 |
Dysphagia (LC-DS) | 6 (30.0) | 12 (19.4) | 0.475 | 0.491 | 23.76 (15.45, 30.05) | 26.56 (15.10, 30.49) | 0.737 (0.259–2.096) | 0.567 |
Peripheral neuropathy (LC-PN) | 7 (35.0) | 14 (22.6) | 1.224 | 0.269 | 23.76 (15.45, 30.05) | 25.95 (13.33, 30.44) | 0.746 (0.286–1.945) | 0.549 |
Alopecia (LC-HR) | 9 (45.0) | 16 (25.8) | 2.629 | 0.105 | 23.30 (13.11, 29.18) | 25.63 (13.33, 29.98) | 0.617 (0.264–1.444) | 0.266 |
Pain in chest (LC-PC) | 9 (45.0) | 22 (35.5) | 0.582 | 0.445 | 20.86 (12.94, 29.18) | 22.11 (8.27, 28.99) | 0.985 (0.439–2.214) | 0.972 |
Pain in aim or should (LC-PA) | 9 (45.0) | 19 (30.6) | 1.386 | 0.239 | 23.30 (15.45, 29.18) | 25.19 (10.02, 29.98) | 0.635 (0.285–1.417) | 0.267 |
Pain in other parts (LC-PO) | 12 (60.0) | 22 (35.5) | 3.745 | 0.053 | 23.30 (14.18, 29.18) | 23.95 (8.78, 29.63) | 0.723 (0.348–1.503) | 0.385 |