Table 6 Comparison of time to deterioration event in different Cpn IgAIgG status
Time to deterioration event of Cpn IgAIgGn(%) | χ2 | P | Time to deterioration of Cpn IgAIgGM (P25, P75) | HR (95% CI) | P | |||||
|---|---|---|---|---|---|---|---|---|---|---|
Cpn IgA-IgG- | Cpn IgA + IgG-/IgA-IgG + | Cpn IgA + IgG + | Cpn IgA-IgG- | Cpn IgA + IgG-/IgA-IgG + | Cpn IgA + IgG + | |||||
QLQ-C30 | ||||||||||
Global health status (QL) | 10 (58.8) | 23 (74.2) | 19 (55.9) | 2.538 | 0.281 | 19.94 (12.94, 29.70) | 11.96 (4.54, 26.55) | 27.45 (13.33, 29.98) | 0.916 (0.645–1.300) | 0.623 |
Functional scales | ||||||||||
Physical functioning (PF) | 11 (64.7) | 23 (74.2) | 15 (44.1) | 6.318 | 0.042 | 15.74 (5.45, 24.84) | 9.99 (4.62, 23.95) | 24.81 (13.67, 29.31) | 0.786 (0.550–1.123) | 0.186 |
Role functioning (RF) | 7 (41.2) | 17 (54.8) | 9 (26.5) | 5.434 | 0.066 | 18.79 (6.60, 29.70) | 18.63 (4.62, 28.16) | 27.45 (14.61, 29.98) | 0.802 (0.515–1.249) | 0.328 |
Emotional functioning (EF) | 9 (52.9) | 9 (29.0) | 8 (23.5) | 4.692 | 0.096 | 15.74 (6.60, 24.84) | 24.38 (11.12, 31.85) | 27.45 (14.61, 30.38) | 0.591 (0.354–0.988) | 0.045 |
Cognitive functioning (CF) | 8 (47.1) | 11 (35.5) | 11 (32.4) | 1.083 | 0.582 | 23.66 (12.94, 29.70) | 24.05 (12.57, 30.70) | 26.56 (14.61, 29.72) | 0.800 (0.500–1.279) | 0.351 |
Social functioning (SF) | 5 (29.4) | 8 (25.8) | 5 (14.7) | 0.399 | 23.66 (14.59, 31.08) | 24.38 (11.12, 31.85) | 28.44 (16.14, 30.38) | 0.717 (0.387–1.328) | 0.290 | |
Symptom scales/items | ||||||||||
Fatigue (FA) | 7 (41.2) | 11 (35.5) | 9 (26.5) | 1.257 | 0.533 | 18.79 (12.94, 29.01) | 23.95 (6.12, 30.70) | 26.56 (13.67, 29.72) | 0.790 (0.481–1.296) | 0.350 |
Nausea and vomiting (NV) | 3 (17.6) | 10 (32.3) | 8 (23.5) | 0.549 | 23.85 (15.74, 31.08) | 24.38 (11.12, 31.85) | 28.44 (16.14, 30.38) | 1.056 (0.593–1.879) | 0.853 | |
Pain (PA) | 10 (58.8) | 16 (51.6) | 13 (38.2) | 2.254 | 0.324 | 14.59 (6.54, 29.01) | 10.28 (5.19, 25.63) | 24.96 (12.91, 29.63) | 0.791 (0.527–1.187) | 0.257 |
Dyspnoea (DY) | 8 (47.1) | 12 (38.7) | 9 (26.5) | 2.345 | 0.310 | 23.66 (12.94, 29.70) | 23.95 (7.00, 30.70) | 27.45 (15.10, 29.98) | 0.745 (0.462–1.201) | 0.226 |
Insomnia (SL) | 11 (64.7) | 12 (38.7) | 15 (44.1) | 3.099 | 0.212 | 15.47 (6.60, 24.84) | 23.95 (9.22, 29.39) | 26.56 (14.78, 29.72) | 0.761 (0.498–1.162) | 0.206 |
Appetite loss (AP) | 6 (35.3) | 10 (32.3) | 10 (29.4) | 0.188 | 0.910 | 22.93 (12.94, 29.70) | 24.38 (9.66, 31.85) | 28.44 (15.10, 30.38) | 0.894 (0.535–1.494) | 0.669 |
Constipation (CO) | 6 (35.3) | 8 (25.8) | 7 (20.6) | 0.519 | 22.93 (12.94, 29.01) | 24.38 (9.66, 31.85) | 27.45 (14.61, 29.98) | 0.743 (0.419–1.321) | 0.312 | |
Diarrhoea (DI) | 4 (23.5) | 12 (38.7) | 6 (17.6) | 0.157 | 23.66 (14.59, 29.70) | 25.30 (11.73, 35.09) | 27.45 (15.10, 29.98) | 0.801 (0.449–1.430) | 0.453 | |
Financial difficulties (FI) | 5 (29.4) | 8 (25.8) | 6 (17.6) | 0.624 | 18.79 (6.60, 29.70) | 24.38 (10.14, 31.85) | 28.44 (16.14, 30.38) | 0.728 (0.400–1.324) | 0.298 | |
QLQ-LC13 | ||||||||||
Dyspnoea (LC-DY) | 11 (64.7) | 17 (54.8) | 15 (44.1) | 2.041 | 0.360 | 12.94 (5.39, 29.01) | 14.36 (5.19, 25.17) | 25.51 (9.95, 29.31) | 0.769 (0.521–1.135) | 0.185 |
Coughing (LC-CO) | 7 (41.2) | 12 (38.7) | 10 (29.4) | 0.930 | 0.628 | 18.79 (6.54, 29.70) | 23.95 (8.05, 29.39) | 27.45 (13.67, 30.30) | 0.773 (0.482–1.239) | 0.285 |
Haemoptysis (LC-HA) | 4 (23.5) | 7 (22.6) | 6 (17.6) | 0.826 | 23.66 (14.59, 29.70) | 25.30 (11.73, 35.09) | 27.45 (15.10, 29.98) | 0.832 (0.441–1.569) | 0.570 | |
Sore mouth (LC-SM) | 4 (23.5) | 8 (25.8) | 5 (14.7) | 0.466 | 23.85 (15.74, 31.08) | 24.38 (11.12, 35.09) | 28.44 (16.14, 30.38) | 0.785 (0.418–1.476) | 0.453 | |
Dysphagia (LC-DS) | 4 (23.5) | 8 (25.8) | 6 (17.6) | 0.738 | 23.66 (14.59, 29.70) | 24.38 (15.21, 31.85) | 28.44 (16.14, 30.38) | 0.810 (0.438–1.500) | 0.503 | |
Peripheral neuropathy (LC-PN) | 5 (29.4) | 8 (25.8) | 8 (23.5) | 0.946 | 23.66 (14.59, 29.70) | 24.38 (15.21, 31.85) | 26.56 (13.72, 29.98) | 0.886 (0.501–1.569) | 0.679 | |
Alopecia (LC-HR) | 7 (41.2) | 11 (35.5) | 7 (20.6) | 2.854 | 0.240 | 22.93 (12.94, 29.01) | 23.95 (10.53, 29.39) | 27.45 (15.10, 29.98) | 0.661 (0.393–1.111) | 0.118 |
Pain in chest (LC-PC) | 7 (41.2) | 15 (48.4) | 9 (26.5) | 3.416 | 0.181 | 18.79 (12.94, 29.01) | 18.46 (6.89, 26.55) | 26.41 (13.67, 29.72) | 0.756 (0.486–1.176) | 0.214 |
Pain in aim or should (LC-PA) | 7 (41.2) | 12 (38.7) | 9 (26.5) | 1.552 | 0.460 | 23.66 (14.59, 29.70) | 23.95 (9.00, 28.16) | 27.45 (13.72, 29.98) | 0.793 (0.487–1.290) | 0.350 |
Pain in other parts (LC-PO) | 9 (52.9) | 13 (41.9) | 12 (35.3) | 1.459 | 0.482 | 22.93 (12.94, 29.01) | 23.03 (8.56, 28.16) | 26.56 (13.33, 29.72) | 0.811 (0.525–1.251) | 0.343 |