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Table 2 Abbreviation: 1,peer-reviewed journal; 2,temperature control; 3,animals were randomly allocated; 4,blind established model; 5, blinded outcome assessment; 6,use of anesthetic without significant intrinsic vascular protection activity; 7, appropriate animal model (diabetic, advanced age or hypertensive); 8,calculation of sample size; 9,statement of compliance with animal welfare regulations; 10,statement of potential conflict of interests

From: The efficacy of extracellular vesicles for acute lung injury in preclinical animal models: a meta-analysis

Study

publication year

1

2

3

4

5

6

7

8

9

10

Total

Buesing, Keely L [29]

2011

1

0

1

0

0

1

1

0

1

0

5

Chang, Chia-Lo [30]

2018

1

1

1

0

1

1

1

0

1

0

7

Chen, W. X [31]

2019

1

1

1

0

0

1

1

0

1

1

7

Chen, W. X [32]

2020

1

1

1

0

0

1

1

0

1

1

7

Deng, H. [33]

2020

1

1

1

0

0

1

1

0

1

0

6

Deng, H [34]

2022

1

1

1

0

0

1

1

0

1

1

7

Huang, R. [35]

2019

1

1

1

0

0

1

1

0

1

1

7

Kaspi, Haggai [36]

2021

1

1

1

0

0

0

1

0

1

0

5

Khatri, M. [37]

2018

1

1

1

0

0

1

1

0

1

1

7

Li, Qing-Chun [38]

2019

1

1

1

0

0

1

1

0

1

1

7

Liu, F. [39]

2021

1

1

1

0

0

1

1

0

1

0

6

Liu, Jian-Hua [40]

2021

1

1

1

0

0

1

1

0

1

1

7

Liu, X. [41]

2021

1

1

1

0

0

1

1

0

1

1

7

Mao, Guan-chao [42]

2021

1

1

1

0

0

0

1

0

1

1

6

Monsel, Antoine [14]

2015

1

1

1

0

0

0

1

0

1

1

6

Morrison, T. J. [43]

2017

1

1

1

0

0

1

1

0

1

1

7

Shi, Meng-meng [44]

2021

1

1

1

0

0

1

1

0

1

1

7

Silva, J. D. [45]

2019

1

1

1

1

1

1

1

0

1

1

9

Silva, J. D. [46]

2021

1

1

1

0

0

1

1

0

1

1

7

Soni, S. [47]

2016

1

1

1

0

1

1

1

0

1

1

8

Tang, Xiao-Dan [48]

2017

1

1

1

0

0

1

1

0

1

1

7

Varkouhi, Amir K. [49]

2019

1

1

1

0

0

1

1

0

1

1

7

Wang, Jiangmei [50]

2020

1

1

1

0

0

1

1

0

1

1

7

Wu, X. [51]

2018

1

1

1

0

0

1

1

0

1

1

7

Xia, L. [52]

2022

1

1

1

0

0

1

1

0

1

1

7

Xu, J. [53]

2022

1

1

1

0

0

1

1

0

1

1

7

Xu, N. [54]

2019

1

1

1

0

0

0

1

0

1

1

6

Xu, Xinyi [55]

2022

1

1

1

0

0

0

1

0

1

1

6

Zhang, L. [56]

2022

1

1

1

1

1

1

1

0

1

1

9

Zhao, R. [57]

2022

1

1

1

0

0

1

1

0

1

1

7

Zhu, Ying-gang [14]

2014

1

1

1

0

0

1

1

0

1

1

7