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Table 1 GO terms, GO pathways and their corresponding P-values and genes for common differentially expressed genes

From: Identification of biomarkers and pathways for the SARS-CoV-2 infections in obstructive sleep apnea patients based on machine learning and proteomic analysis

Category

GO ID

GO pathways

P-value

Genes

GO Biological Process

GO:0033483

gas homeostasis

9.54E-06

CAV1;HIF1A

GO:0032077

positive regulation of deoxyribonuclease activity

0.003495399

PCNA

GO:0070836

caveola assembly

0.003495399

CAV1

GO:0072584

caveolin-mediated endocytosis

0.003495399

CAV1

GO:1,903,377

negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway

0.003495399

HIF1A

GO:0048550

negative regulation of pinocytosis

0.003495399

CAV1

GO:0014037

Schwann cell differentiation

0.003495399

NF1

GO:0006880

intracellular sequestering of iron ion

0.003495399

FTH1

GO:1,901,979

regulation of inward rectifier potassium channel activity

0.003495399

CAV1

GO:0061419

positive regulation of transcription from RNA polymerase II promoter in response to hypoxia

0.003495399

HIF1A

GO Cellular Component

GO:0000779

condensed chromosome, centromeric region

0.006979474

NCAPD2

GO:0044754

autolysosome

0.006979474

FTH1

GO:0005767

secondary lysosome

0.01114544

FTH1

GO:0031092

platelet alpha granule membrane

0.011838189

CD109

GO:0016514

SWI/SNF complex

0.013222334

RB1

GO:0042383

sarcolemma

0.03580243

CAV1

GO:0000793

condensed chromosome

0.03715538

NCAPD2

GO:1,904,724

tertiary granule lumen

0.037831194

FTH1

GO:0005901

caveola

0.041203662

CAV1

GO:0005776

autophagosome

0.047246461

FTH1

GO Molecular Function

GO:0032135

DNA insertion or deletion binding

0.003495399

PCNA

GO:0035035

histone acetyltransferase binding

9.48E-05

PCNA;HIF1A

GO:0005113

patched binding

0.004890388

CAV1

GO:0032405

MutLalpha complex binding

0.004890388

PCNA

GO:0008199

ferric iron binding

0.004890388

FTH1

GO:0004322

ferroxidase activity

0.004890388

FTH1

GO:0016724

oxidoreductase activity, acting on metal ions, oxygen as acceptor

0.004890388

FTH1

GO:0050998

nitric-oxide synthase binding

0.004890388

CAV1

GO:0019870

potassium channel inhibitor activity

0.006283564

CAV1

GO:0008429

phosphatidylethanolamine binding

0.006283564

NF1