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Table 1 Characteristics of patients with high altitude pulmonary edema on admission (n%; x ± s; median (IQR))

From: Effect of furosemide in the treatment of high-altitude pulmonary edema

 

Non-furosemide group (n=64)

Furosemide group (n=209)

P Value

Mean age (years)

35.64 ± 10.98

33.69 ± 10.87

0.212

Gender (male%)

55.00 (85.94%)

179.00 (85.65%)

0.953

Body Mass Index (kg/m2)

23.08 ± 1.42

22.81 ± 1.57

0.226

Altitude before entering the high altitude area (m)

1246.00 ± 554.31

1219.65 ± 453.40

0.701

Altitude at the time of onset (m)

3728.42 ± 70.49

3737.26 ± 130.48

0.604

Time of onset after entering high altitude area (day)

4.19 ± 2.00

4.29 ± 1.94

0.708

Current smoker (%)

15.00 (23.44%)

53.00 (25.36%)

0.756

Alcohol abuse (%)

22.00 (34.38%)

73.00 (34.93%)

0.935

Past history

   

 Hypertension (%)

3.00 (4.69%)

7.00 (3.35%)

0.618

 Diabetes mellitus (%)

2.00 (3.13%)

8.00 (3.83%)

0.793

 Coronary heart disease (%)

0.00 (0.00%)

0.00 (0.00%)

/

 Heart failure (%)

0.00 (0.00%)

0.00 (0.00%)

/

 Cerebrovascular disease (%)

0.00 (0.00%)

1.00 (0.48%)

1.000

 Peripheral vascular disease (%)

0.00 (0.00%)

1.00 (0.48%)

1.000

 COPD (%)

0.00 (0.00%)

0.00 (0.00%)

/

 Connective tissue disease (%)

0.00 (0.00%)

0.00 (0.00%)

/

 Peptic ulcer (%)

0.00 (0.00%)

0.00 (0.00%)

/

 Chronic Liver Disease (%)

0.00 (0.00%)

0.00 (0.00%)

/

 Chronic renal failure (%)

0.00 (0.00%)

0.00 (0.00%)

/

 Solid tumor (%)

0.00 (0.00%)

0.00 (0.00%)

/

 Leukaemia (%)

0.00 (0.00%)

1.00 (0.48%)

1.000

 Lymphoma (%)

0.00 (0.00%)

0.00 (0.00%)

/

 HIV (%)

0.00 (0.00%)

0.00 (0.00%)

/

Vital sign

   

 Body temperature (℃)

36.60 ± 0.42

36.59 ± 0.48

0.918

 Heart rate (beat per minute)

98.95 ± 17.54

92.86 ± 17.47

0.015*

 Respiratory rate (breaths per minute)

21.23 ± 1.83

21.05 ± 3.84

0.722

 Systolic pressure (mmHg)

117.02 ± 16.55

117.68 ± 17.27

0.785

 Diastolic pressure (mmHg)

81.25 ± 12.94

78.92 ± 12.74

0.204

 Mean arterial pressure (mmHg)

93.17 ± 12.88

91.84 ± 13.02

0.475

Laboratory index

   

 White blood cell (×109/l)

9.51 ± 3.41

10.27 ± 4.01

0.169

 C-reactive protein (µg/ml)

8.00 (8.12)

7.00 (6.50)

0.435

 Procalcitonin (ng/ml)

0.24 ± 0.06

0.26 ± 0.07

0.032*

 Hemoglobin (g/l)

151.88 ± 25.24

157.85 ± 22.49

0.072

 Hematocrit (%)

44.95 ± 7.09

46.95 ± 6.31

0.032*

 Platelet (×109/l)

198.01 ± 69.28

236.57 ± 69.88

< 0.001*

 Alanine aminotransferase (U/l)

34.00 (26.75)

28.00 (21.50)

0.918

 Total bilirubin (µmol/l)

17.46 ± 12.35

17.96 ± 8.38

0.711

 Albumin (g/l)

43.67 ± 5.29

43.80 ± 5.49

0.861

 Prealbumin (g/l)

221.45 ± 68.90

213.07 ± 59.33

0.342

 Serum creatinine (µmol/l)

88.68 ± 25.64

85.40 ± 26.48

0.383

 Blood urea nitrogen (mmol/l)

6.32 ± 2.64

6.34 ± 2.17

0.942

 Blood potassium (mmol/l)

3.57 ± 0.39

3.73 ± 0.44

0.008*

 Blood glucose (mmol/l)

6.11 ± 2.59

5.82 ± 1.89

0.328

 D-dimer (mg/l)

0.47 (0.38)

0.48 (0.41)

0.396

 Potential of hydrogen

7.43 ± 0.04

7.42 ± 0.05

0.255

 PaO2 (mmHg)

42.55 ± 6.69

42.86 ± 7.56

0.769

 Oxygenation index

202.60 ± 31.84

204.08 ± 35.99

0.769

  1. Note: COPD: Chronic obstructive pulmonary disease. HIV: Acquired Immune Deficiency Syndrome. *P < 0.05 was considered statistically signifcant