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Fig. 2 | BMC Pulmonary Medicine

Fig. 2

From: IRF4-mediated Treg phenotype switching can aggravate hyperoxia-induced alveolar epithelial cell injury

Fig. 2

Abnormal transdifferentiation and inflammatory response induced by hyperoxia in mice. a Western blot analysis of SP-C, T1α, and IRF4 expression in the mouse lung tissues of the normoxia and hyperoxia groups. β-actin was used as the loading control. b ELISA of IL-6 and IL-17 A expression in the mouse lung tissues of each group. c Correlation analysis of IRF4 with IL-6 and IL-17 A. The representative data from five independent experiments. Data are presented as mean ± SD (n = 5, t-test one-way); *P < 0.05 and **P < 0.01 vs. normoxia group

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