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Fig. 3 | BMC Pulmonary Medicine

Fig. 3

From: IRF4-mediated Treg phenotype switching can aggravate hyperoxia-induced alveolar epithelial cell injury

Fig. 3

Hyperoxia-induced conversion of FOXP3 + Tregs to FOXP3 + RORγt + Tregs in mouse lung tissues. a Flow cytometry analysis of FOXP+ Tregs in the mouse lung tissues of the normoxia and hyperoxia groups. b Flow cytometry analysis of FOXP3+RORγt+ Tregs in the mouse lung tissues of the normoxia and hyperoxia groups. c Correlation analysis of FOXP3+ Tregs with SP-C and T1α. The representative data from five independent experiments. Data are presented as mean ± SD (n = 5, t-test one-way); *P < 0.05 and **P < 0.01 vs. normoxia group

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