Table 1 Demographics of lung cancer patients and healthy controls
Characteristics | Patients, n(%) | Controls, n(%) | P |
|---|---|---|---|
(n = 498) | (n = 213) | ||
Sex | |||
 Male | 394(79.1) | 80(37.6) | 0.000* |
 Female | 104(20.9) | 133(62.4) | |
Age (years) | |||
 < 57 | 242(48.6) | 74(34.7) | 0.000* |
 ≥ 57 | 256(51.4) | 139(65.3 | |
Histology | |||
 NSCLC | 429(86.1) |  |  |
 SCLC | 69(13.9) |  |  |
 SCC | 189(37.9) |  |  |
 ADC | 217(43.6) |  |  |
 Othera | 23(4.6) |  |  |
Stage (NSCLC) | |||
 I, II | 13(3.0) |  |  |
 III, IV | 416(97.0) |  |  |
Stage (SCLC) | |||
 Limited | 36(52.2) |  |  |
 Extensive | 33(47.8) |  |  |
Regimen | |||
 Regimen1 | 192(41.4) |  |  |
 Regimen2 | 68(14.6) |  |  |
 Regimen3 | 137(29.3) |  |  |
 Regimen4 | 27(5.8) |  |  |
 Regimen5 | 29(6.2) |  |  |
 Otherb | 14(3.0) |  |  |
Chemotherapy response | 467 | Â | Â |
 Responder | 283(60.6) |  |  |
 Non-responder | 184(39.4) |  |  |
Overall toxicity | 467 | Â | Â |
 Grade 0–2 | 286(61.2) |  |  |
 Grade 3–4 | 181(38.8) |  |  |
Gastrointestinal toxicity | 467 | Â | Â |
 Grade 0–2 | 366(78.4) |  |  |
 Grade 3–4 | 101(21.6) |  |  |
Hematological toxicity | 467 | Â | Â |
 Grade 0–2 | 353(75.6) |  |  |
 Grade 3–4 | 114(24.4) |  |  |