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Table 4 CCND1 rs9344 and lung cancer risk under the random- and fixed- effects model

From: Association of CCND1 rs9344 polymorphism with lung cancer susceptibility and clinical outcomes: a case-control study

Genetic model

Random-effects model

Fixed-effects model

Publication bias (P)

Test of association

Test of heterogeneity

Test of association

Test of heterogeneity

OR

95%CI

P

P

I2(%)

OR

95%CI

P

P

I2(%)

Egger’s test

Begg’s test

GA vs. GG

1.02

0.85–1.23

0.847

0.0052

60.10%

1.00

0.9207–1.0957

0.9215

0.01%

60.10%

0.7850

0.3502

AA vs. GG

1.01

0.77–1.32

0.943

< 0.0001

73.10%

1.06

0.9522–1.1727

0.2989

< 0.0001

73.10%

0.6488

1.0000

AA vs. GA

1.00

0.81–1.24

0.983

0.0002

69.90%

1.08

0.9833–1.1788

0.1106

0.0002

69.90%

0.3409

0.2758

AA + GA vs. GG

1.04

0.85–1.26

0.726

0.0005

68.20%

1.06

0.9755–1.1478

0.1735

0.0005

68.20%

0.7651

0.8763

GA vs. AA + GG

1.01

0.86–1.17

0.976

0.0025

63.20%

0.99

0.9175–1.0590

0.6938

0.0025

63.20%

0.7450

0.5334

AA vs. GA + GG

1.00

0.81–1.25

0.942

< 0.0001

73.80%

1.09

0.9977–1.1844

0.0564

< 0.0001

73.80%

0.3367

0.5334

allelic A vs. G

1.02

0.90–1.16

0.757

< 0.0001

73.30%

1.05

1.0005–1.1074

0.0478

< 0.0001

73.30%

0.5028

0.8763

  1. Abbreviations n number, OR Odds ratio, CI Confidence interval