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  1. There are not enough data on the epidemiology of asthma in the Kingdom of Saudi Arabia (KSA). We analyzed data from a national household survey conducted in KSA in 2013 to estimate prevalence, associated risk ...

    Authors: Maziar Moradi-Lakeh, Charbel El Bcheraoui, Farah Daoud, Marwa Tuffaha, Hannah Kravitz, Mohammad Al Saeedi, Mohammed Basulaiman, Ziad A. Memish, Mohammad A. AlMazroa, Abdullah A. Al Rabeeah and Ali H. Mokdad
    Citation: BMC Pulmonary Medicine 2015 15:77
  2. Even through narrowing of the upper-airway plays an important role in the generation of obstructive sleep apnea (OSA), the peripheral airways is implicated in pre-obese and obese OSA patients, as a result of d...

    Authors: Arikin Abdeyrim, Yongping Zhang, Nanfang Li, Minghua Zhao, Yinchun Wang, Xiaoguang Yao, Youledusi Keyoumu and Ting Yin
    Citation: BMC Pulmonary Medicine 2015 15:76
  3. Propionibacterium acnes was found in lungs and lymph nodes of patients with sarcoidosis and may induce hypersensitivity type granuloma formation. Data regarding the immune response to P. acnes of European sarcoid...

    Authors: Jonas Christian Schupp, Sandrine Tchaptchet, Niklas Lützen, Peggy Engelhard, Joachim Müller-Quernheim, Marina A Freudenberg and Antje Prasse
    Citation: BMC Pulmonary Medicine 2015 15:75
  4. Quantitative computed tomography (CT) analysis has been proposed as a means of objectively assessing fibrotic interstitial pneumonia (IP) including idiopathic pulmonary fibrosis (IPF). We investigated whether ...

    Authors: Kiminobu Tanizawa, Tomohiro Handa, Sonoko Nagai, Toyohiro Hirai, Takeshi Kubo, Tsuyoshi Oguma, Isao Ito, Yutaka Ito, Kizuku Watanabe, Kensaku Aihara, Kohei Ikezoe, Toru Oga, Kazuo Chin, Takateru Izumi and Michiaki Mishima
    Citation: BMC Pulmonary Medicine 2015 15:74
  5. We have recently demonstrated the efficacy of balance training in addition to Pulmonary Rehabilitation (PR) at improving measures of balance associated with an increased risk of falls in individuals with Chron...

    Authors: Samantha L. Harrison, Marla K. Beauchamp, Kathryn Sibley, Tamara Araujo, Julia Romano, Roger S. Goldstein and Dina Brooks
    Citation: BMC Pulmonary Medicine 2015 15:73
  6. Secretoglobin (SCGB) 3A2, a cytokine-like secretory protein of small molecular weight, is predominantly expressed in airway epithelial cells. While SCGB3A2 is known to have anti-inflammatory, growth factor, an...

    Authors: Yan Cai, Mitsuhiro Yoneda, Takeshi Tomita, Reiko Kurotani, Minoru Okamoto, Taketomo Kido, Hiroyuki Abe, Wayne Mitzner, Arjun Guha and Shioko Kimura
    Citation: BMC Pulmonary Medicine 2015 15:72
  7. Although sedation is often required for agitated patients undergoing noninvasive ventilation (NIV), reports on its practical use have been few. This study aimed to evaluate the efficacy and safety of sedation ...

    Authors: Takeshi Matsumoto, Keisuke Tomii, Ryo Tachikawa, Kojiro Otsuka, Kazuma Nagata, Kyoko Otsuka, Atsushi Nakagawa, Michiaki Mishima and Kazuo Chin
    Citation: BMC Pulmonary Medicine 2015 15:71
  8. It has been recognized that despite previous stability some patients with idiopathic pulmonary fibrosis (IPF) experience acute clinical deteriorations called acute exacerbations of idiopathic pulmonary fibrosi...

    Authors: Frunze Petrosyan, Daniel A. Culver and Anita J. Reddy
    Citation: BMC Pulmonary Medicine 2015 15:70
  9. Chronic obstructive pulmonary disease (COPD) patients often have dysphagia through age and several co-morbidities, leading to aspiration pneumonia (AsP). COPD patients also have increased risk of developing co...

    Authors: Yasuhiro Yamauchi, Hideo Yasunaga, Hiroki Matsui, Wakae Hasegawa, Taisuke Jo, Kazutaka Takami, Kiyohide Fushimi and Takahide Nagase
    Citation: BMC Pulmonary Medicine 2015 15:69
  10. Silibinin has been known for its role in anti-cancer and radio-protective effect. Radiation therapy for treating lung cancer might lead to late-phase pulmonary inflammation and fibrosis. Thus, this study aimed...

    Authors: Yeonghoon Son, Hae June Lee, Jin Kyung Rho, Soo Young Chung, Chang Geun Lee, Kwangmo Yang, Sung Ho Kim, Minyoung Lee, In Sik Shin and Joong Sun Kim
    Citation: BMC Pulmonary Medicine 2015 15:68
  11. Staphylococcus aureus (SA) is the most prevalent organism infecting the respiratory tract of CF children, and remains the second most prevalent organism in CF adults. During early childhood, SA infections are ass...

    Authors: Heather G. Ahlgren, Andrea Benedetti, Jennifer S. Landry, Joanie Bernier, Elias Matouk, Danuta Radzioch, Larry C. Lands, Simon Rousseau and Dao Nguyen
    Citation: BMC Pulmonary Medicine 2015 15:67
  12. Silicosis is an occupational disease for which no effective treatment is currently known. Systemic administration of bone marrow-derived mononuclear cells (BMDMCs) has shown to be safe in lung diseases. Howeve...

    Authors: Marcelo M. Morales, Sérgio A. L. Souza, Luiz Paulo Loivos, Marina A. Lima, Amir Szklo, Leandro Vairo, Taís H. K. Brunswick, Bianca Gutfilen, Miquéias Lopes-Pacheco, Alberto J. Araújo, Alexandre P. Cardoso, Regina C. Goldenberg, Patricia R. M. Rocco, Lea M. B. Fonseca and José R. Lapa e Silva
    Citation: BMC Pulmonary Medicine 2015 15:66
  13. Heliox is a mixture of oxygen and helium which reduces airway resistance in patients with airway obstruction. In clinical practice, patients breathing spontaneously receive heliox via an open circuit. Recently...

    Authors: Ivana Jurickova, Karel Roubík and Martin Muller
    Citation: BMC Pulmonary Medicine 2015 15:65
  14. Systemic inflammation is present in chronic obstructive pulmonary disease (COPD). A whey peptide-based enteral diet reduce inflammation in patients with COPD, but its effect on COPD development has not been de...

    Authors: Koichi Tomoda, Kaoru Kubo, Kazuo Dairiki, Taketo Yamaji, Yoshifumi Yamamoto, Yasue Nishii, Atsuhiro Nakamura, Masanori Yoshikawa, Kaoru Hamada and Hiroshi Kimura
    Citation: BMC Pulmonary Medicine 2015 15:64
  15. Exercise has been studied as a prognostic marker for patients with cystic fibrosis (CF), as well as a tool for improving their quality of life and analyzing lung disease. In this context, the aim of the presen...

    Authors: Paloma Lopes Francisco Parazzi, Fernando Augusto de Lima Marson, Maria Angela Gonçalves de Oliveira Ribeiro, Celize Cruz Bresciani de Almeida, Luiz Cláudio Martins, Ilma Aparecida Paschoal, Adyleia Aparecida Dalbo Contrera Toro, Camila Isabel Santos Schivinski and Jose Dirceu Ribeiro
    Citation: BMC Pulmonary Medicine 2015 15:63
  16. Recent vasodilating drugs have improved prognosis of Pulmonary arterial hypertension (PAH). Some reports describe the merits of combination therapies for PAH, and this study evaluated the efficacy and safety o...

    Authors: Mai Kimura, Yuichi Tamura, Makoto Takei, Tsunehisa Yamamoto, Tomohiko Ono, Jun Fujita, Masaharu Kataoka, Masataka Kuwana, Toru Satoh and Keiichi Fukuda
    Citation: BMC Pulmonary Medicine 2015 15:62
  17. The impact of bronchiectasis on sedentary behaviour and physical activity is unknown. It is important to explore this to identify the need for physical activity interventions and how to tailor interventions to...

    Authors: Judy M Bradley, Jason J Wilson, Kate Hayes, Lisa Kent, Suzanne McDonough, Mark A Tully, Ian Bradbury, Alison Kirk, Denise Cosgrove, Rory Convery, Martin Kelly, Joseph Stuart Elborn and Brenda O’Neill
    Citation: BMC Pulmonary Medicine 2015 15:61
  18. Protective ventilation with lower tidal volume (VT) and higher positive end-expiratory pressure (PEEP) reduces the negative additive effects of mechanical ventilation during systemic inflammatory response syndrom...

    Authors: Jesper Sperber, Miklós Lipcsey, Anders Larsson, Anders Larsson, Jan Sjölin and Markus Castegren
    Citation: BMC Pulmonary Medicine 2015 15:60
  19. The best clinical practice to investigate aerobic fitness includes measurements obtained during cardiopulmonary exercise testing (CPET), however it remains an underutilised clinical measure in cystic fibrosis ...

    Authors: Daniela Savi, Marcello Di Paolo, Nicholas Simmonds, Paolo Onorati, Mattia Internullo, Serena Quattrucci, Banya Winston, Pierantonio Laveneziana and Paolo Palange
    Citation: BMC Pulmonary Medicine 2015 15:59
  20. Little is known about the relationship between hemoglobin concentrations, functional status and health related quality of life (HRQL) in chronic obstructive pulmonary disease (COPD). Our aim was to investigate...

    Authors: Marcello Ferrari, Lorenzo Manea, Kamel Anton, Paola Bruzzone, Mara Meneghello, Francesco Zamboni, Luigi Purgato, Lucia Cazzoletti, Pietro Ferrari and Renato Testi
    Citation: BMC Pulmonary Medicine 2015 15:58
  21. Previous studies indicated that the single nucleotide polymorphisms (SNPs) in TLR9 gene might be associated with Tuberculosis (TB) risk. However, the results are inconsistent and inconclusive.

    Authors: Zhi Chen, Wei Wang, Jianqin Liang, Jinhe Wang, Shisheng Feng and Guangyu Zhang
    Citation: BMC Pulmonary Medicine 2015 15:57
  22. Physical training has been shown to improve exercise capabilities in patients with asthma. Most studies focused on children and younger adults. Previously, the maximum program duration was six months. It is no...

    Authors: Andreas Meyer, Sabine Günther, Timm Volmer, Karin Taube and Hans J Baumann
    Citation: BMC Pulmonary Medicine 2015 15:56
  23. After the SMART trial evaluating the safety of salmeterol (long-acting beta-2-agonist (LABA)) in asthma patients, regulatory actions were taken to promote a guideline-adherent prescribing of LABA only to patie...

    Authors: Marietta Rottenkolber, Rainald Fischer, Luisa Ibáñez, Joan Fortuny, Robert Reynolds, Justyna Amelio, Roman Gerlach, Martin Tauscher, Petra Thürmann, Joerg Hasford and Sven Schmiedl
    Citation: BMC Pulmonary Medicine 2015 15:55
  24. Pompe disease is a progressive metabolic myopathy. Involvement of respiratory muscles leads to progressive pulmonary dysfunction, particularly in supine position. Diaphragmatic weakness is considered to be the...

    Authors: Stephan CA Wens, Pierluigi Ciet, Adria Perez-Rovira, Karla Logie, Elizabeth Salamon, Piotr Wielopolski, Marleen de Bruijne, Michelle E Kruijshaar, Harm AWM Tiddens, Pieter A van Doorn and Ans T van der Ploeg
    Citation: BMC Pulmonary Medicine 2015 15:54
  25. During the pathological destruction of lung tissue, neutrophil elastase (NE) degrades elastin, one of the major constituents of lung parenchyma. However there are no non-invasive methods to quantify NE degrada...

    Authors: Jacob H Kristensen, Morten A Karsdal, Jannie MB Sand, Nicholas Willumsen, Claudia Diefenbach, Birte Svensson, Per Hägglund and Diana J Oersnes-Leeming
    Citation: BMC Pulmonary Medicine 2015 15:53
  26. Dietary nitrate supplementation has been shown to decrease the oxygen cost of exercise and prolong exercise tolerance, as measured by sub-maximal exercise endurance distance and time at 85% V̇O2max, in both elite...

    Authors: Paul Leong, Jane E Basham, Theresa Yong, Adrian Chazan, Paul Finlay, Sara Barnes, Phillip G Bardin and Donald Campbell
    Citation: BMC Pulmonary Medicine 2015 15:52
  27. This pilot study, conducted on a 1/97th representative sample of French claims data, prepared a project to assess the effectiveness of Montelukast (MTL-4) as add-on therapy for asthma in infants (6–24 months) ...

    Authors: Manon Belhassen, Gérard de Pouvourville, Laurent Laforest, Jacques Brouard, Jacques de Blic, Brigitte Fauroux, Valérie Laigle, Céline Chanut-Vogel, Liliane Lamezec and Eric Van Ganse
    Citation: BMC Pulmonary Medicine 2015 15:51
  28. Oxidative stress (OS) and reduced nitric oxide (NO) bioavailability contribute to the pathogenesis of pulmonary hypertension (PH). Whether there are associations between OS and NO signaling biomarkers and whet...

    Authors: Shuai Zhang, Ting Yang, Xiaomao Xu, Meng Wang, Linye Zhong, Yuanhua Yang, Zhenguo Zhai, Fei Xiao and Chen Wang
    Citation: BMC Pulmonary Medicine 2015 15:50
  29. Cystic fibrosis (CF) is a genetic disease characterized by complex polymicrobial communities within the lower respiratory tract. S. pneumoniae, while a well-defined pathogen in the general population, has rarely ...

    Authors: Christina S Thornton, Erin L Brown, Joenel Alcantara, Harvey R Rabin and Michael D Parkins
    Citation: BMC Pulmonary Medicine 2015 15:49
  30. Dampness and mould exposure have been repeatedly associated with respiratory health. However, less is known about the specific agents provoking or arresting health effects in adult populations. We aimed to ass...

    Authors: Christina Tischer, Jan-Paul Zock, Maria Valkonen, Gert Doekes, Stefano Guerra, Dick Heederik, Deborah Jarvis, Dan Norbäck, Mario Olivieri, Jordi Sunyer, Cecilie Svanes, Martin Täubel, Elisabeth Thiering, Giuseppe Verlato, Anne Hyvärinen and Joachim Heinrich
    Citation: BMC Pulmonary Medicine 2015 15:48
  31. Spiromax® is a novel dry-powder inhaler containing formulations of budesonide plus formoterol (BF). The device is intended to provide dose equivalence with enhanced user-friendliness compared to BF Turbuhaler®...

    Authors: Wahida Azouz, Philip Chetcuti, Harold Hosker, Dinesh Saralaya and Henry Chrystyn
    Citation: BMC Pulmonary Medicine 2015 15:47
  32. Neurohumoral activation is present in COPD and might provide a link between pulmonary and systemic effects, especially cardiovascular disease. Because long acting inhaled β-agonists reduce hyperinflation, they...

    Authors: Helge Haarmann, Cordula Mohrlang, Uta Tschiesner, David B Rubin, Thore Bornemann, Karin Rüter, Slavtcho Bonev, Tobias Raupach, Gerd Hasenfuß and Stefan Andreas
    Citation: BMC Pulmonary Medicine 2015 15:46
  33. Respiratory syncytial virus (RSV) lower respiratory tract infection (LRI) during infancy has been consistently associated with an increased risk of childhood asthma. In addition, evidence supports that this re...

    Authors: Emma K Larkin, Tebeb Gebretsadik, Martin L Moore, Larry J Anderson, William D Dupont, James D Chappell, Patricia A Minton, R Stokes Peebles Jr, Paul E Moore, Robert S Valet, Donald H Arnold, Christian Rosas-Salazar, Suman R Das, Fernando P Polack and Tina V Hartert
    Citation: BMC Pulmonary Medicine 2015 15:45
  34. COPD is largely under-diagnosed and once diagnosed usually at a late stage. Early diagnosis is thoroughly recommended but most attempts failed as the disease is marginally known and screening marginally accept...

    Authors: Nicolas Molinari, Mathieu Abou-Badra, Grégory Marin, Chin-Long Ky, Noemi Amador, Anne Sophie Gamez, Isabelle Vachier and Arnaud Bourdin
    Citation: BMC Pulmonary Medicine 2015 15:44
  35. Adherence to treatment is often reported to be low in children with cystic fibrosis. Adherence in cystic fibrosis is an important research area and more research is needed to better understand family barriers ...

    Authors: Nicola A Goodfellow, Ahmed F Hawwa, Alastair JM Reid, Rob Horne, Michael D Shields and James C McElnay
    Citation: BMC Pulmonary Medicine 2015 15:43
  36. Although asthma morbidity can be prevented through long-term controller medication, most patients with persistent asthma do not take their daily inhaled corticosteroid. The objective of this study was to gathe...

    Authors: Sandra Peláez, Alexandrine J Lamontagne, Johanne Collin, Annie Gauthier, Roland M Grad, Lucie Blais, Kim L Lavoie, Simon L Bacon, Pierre Ernst, Hélène Guay, Martha L McKinney and Francine M Ducharme
    Citation: BMC Pulmonary Medicine 2015 15:42
  37. Irisin, a recently discovered myokine, is assumed to be secreted by muscle cells in response to exercise and is involved in the regulation of energy metabolism by browning white adipose tissue cells. However, ...

    Authors: Nils Kerstholt, Ralf Ewert, Matthias Nauck, Thomas Spielhagen, Tom Bollmann, Beate Stubbe, Stephan B Felix, Henri Wallaschofski, Sven Gläser and Nele Friedrich
    Citation: BMC Pulmonary Medicine 2015 15:41
  38. Pulmonary arterial hypertension (PAH) is a progressive disorder characterized by hypertension in the pulmonary arteries. PAH leads to symptoms such as shortness of breath, dizziness, leg edema and chest pain, ...

    Authors: Roselien Buys, Andrea Avila and Véronique A Cornelissen
    Citation: BMC Pulmonary Medicine 2015 15:40
  39. In adults, overweight is associated with reduced lung function, in children evidence on this association is conflicting. We examined the association of body mass index (BMI) and waist circumference (WC) at age...

    Authors: Marga B Bekkers, Alet H Wijga, Ulrike Gehring, Gerard H Koppelman, Johan C de Jongste, Henriette A Smit and Bert Brunekreef
    Citation: BMC Pulmonary Medicine 2015 15:39
  40. There is a paucity of clinical and histopathological data about HIV-associated lymphocytic interstitial pneumonitis (LIP) in adults from HIV endemic settings. The role of Ebstein-Barr virus (EBV) in the pathog...

    Authors: Richard N van Zyl-Smit, Jashira Naidoo, Helen Wainwright, Quanita Said-Hartley, Malika Davids, Hillel Goodman, Sean Rogers and Keertan Dheda
    Citation: BMC Pulmonary Medicine 2015 15:38
  41. The treatment landscape for idiopathic pulmonary fibrosis, a devastating lung disease, is changing. To investigate the effectiveness of treatments for idiopathic pulmonary fibrosis we undertook a systematic re...

    Authors: Emma Loveman, Vicky R Copley, David A Scott, Jill L Colquitt, Andrew J Clegg and Katherine MA O’Reilly
    Citation: BMC Pulmonary Medicine 2015 15:37
  42. The morbidity associated with severe uncontrolled asthma is disproportionately higher in low- and middle-income countries than in high-income countries. The aim of this study was to describe the phenotypic cha...

    Authors: Wenderson Clay Correia de Andrade, Laura Maria de Lima Belizário Facury Lasmar, Cristiane de Abreu Tonelli Ricci, Paulo Augusto Moreira Camargos and Álvaro A Cruz
    Citation: BMC Pulmonary Medicine 2015 15:36
  43. Asthma is a common chronic disease among young adults, and several studies have reported increased mortality rates in patients with asthma. However, no study has described sudden unexpected death in a nationwi...

    Authors: Anders Juul Gullach, Bjarke Risgaard, Thomas Hadberg Lynge, Reza Jabbari, Charlotte Glinge, Stig Haunsø, Vibeke Backer, Bo Gregers Winkel and Jacob Tfelt-Hansen
    Citation: BMC Pulmonary Medicine 2015 15:35
  44. Thorax is the common place to develop Castleman disease (CD), but there is no systemic clinical analysis for intrathoracic CD.

    Authors: Jin mei Luo, Shan Li, Hui Huang, Jian Cao, Kai Xu, Ya lan Bi, Rui e Feng, Cheng Huang, Ying zhi Qin, Zuo jun Xu and Yi Xiao
    Citation: BMC Pulmonary Medicine 2015 15:34
  45. Skin prick tests (SPT) are widely used both in clinical diagnostics and in research. The standardization of allergen extracts is well documented to be crucial for the validity of SPT, whereas less emphasis has...

    Authors: Gert F Thomsen, Vivi Schlünssen, Lars R Skadhauge, Tine Halsen Malling, David L Sherson, Øyvind Omland and Torben Sigsgaard
    Citation: BMC Pulmonary Medicine 2015 15:33
  46. Deleted in malignant brain tumors 1 (DMBT1) is an innate defence protein expressed in the lungs of preterm infants and adults. Recent studies showed that DMBT1 is important in angiogenesis and can bind to differe...

    Authors: Hanna Müller, Christian Nagel, Christel Weiss, Jan Mollenhauer and Johannes Poeschl
    Citation: BMC Pulmonary Medicine 2015 15:32
  47. As part of an investigation into the respiratory health in children conducted in Torino, northwestern Italy, our aim was to assess development in lung function from childhood to adolescence, and to assess chan...

    Authors: Pavilio Piccioni, Roberta Tassinari, Aurelia Carosso, Carlo Carena, Massimiliano Bugiani and Roberto Bono
    Citation: BMC Pulmonary Medicine 2015 15:31
  48. Fibered confocal fluorescence microscopy (FCFM) allows in vivo investigation of pulmonary microstructures. However, the bronchial epithelium can only be imaged using exogenous fluorophores. The objective of this ...

    Authors: Bérengère Obstoy, Mathieu Salaun, Liana Veresezan, Richard Sesboüé, Pierre Bohn, François-Xavier Boland and Luc Thiberville
    Citation: BMC Pulmonary Medicine 2015 15:30
  49. The approach to palliative treatment of malignant pleural effusion (MPE) should be individualized because these patients generally have poor survival. Our study aimed to develop a model to identify prognostic ...

    Authors: Mauro Musa Zamboni, Cyro Teixeira da Silva Jr, Rodrigo Baretta, Edson Toscano Cunha and Gilberto Perez Cardoso
    Citation: BMC Pulmonary Medicine 2015 15:29
  50. Patients with pulmonary arteriovenous malformations usually complain of dyspnoea upon exertion, fatigue or migraine, or may be asymptomatic. We describe a patient with an unreported manifestation of a pulmonar...

    Authors: Etienne-Marie Jutant, Philippe Puyo, Mostafa El Hajjam, Sandra Blivet, Emmanuel Houdart, Michel Aubier, Pascal Lacombe and Thierry Chinet
    Citation: BMC Pulmonary Medicine 2015 15:28

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