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  1. Mechanical ventilation augments lung inflammation resulting from exposure to microbial products. The objective of this study was to test the hypothesis that ventilator-associated immune modulation requires MyD...

    Authors: Carrie D Chun, W Conrad Liles, Charles W Frevert, Robb W Glenny and William A Altemeier
    Citation: BMC Pulmonary Medicine 2010 10:57
    Content type: Research article Published on:

  2. Pseudomonas aeruginosa infections are associated with progressive life threatening decline of lung function in cystic fibrosis sufferers. Growth of Ps. aeruginosa releases a "grape-like" odour that has been iden...

    Authors: Amy J Scott-Thomas, Mona Syhre, Philip K Pattemore, Michael Epton, Richard Laing, John Pearson and Stephen T Chambers
    Citation: BMC Pulmonary Medicine 2010 10:56
    Content type: Research article Published on:

  3. We examined the influence of overweight and obesity on pulmonary function, exercise tolerance, quality of life and response to pulmonary rehabilitation in COPD.

    Authors: Francesco Sava, Louis Laviolette, Sarah Bernard, Marie-Josée Breton, Jean Bourbeau and François Maltais
    Citation: BMC Pulmonary Medicine 2010 10:55
    Content type: Research article Published on:

  4. Kikuchi-Fujimoto's disease (KFD), also called histiocytic necrotizing lymphadenitis, is a rare, idiopathic and self-limited condition usually characterized by cervical lymphadenopathy and fever, most often aff...

    Authors: Alberto Garcia-Zamalloa, Jorge Taboada-Gomez, Pilar Bernardo-Galán, Fernandez-Martinez Magdalena, Laura Zaldumbide-Dueñas and Mario Ugarte-Maiztegui
    Citation: BMC Pulmonary Medicine 2010 10:54
    Content type: Case report Published on:

  5. Pulmonary surfactant D (SP-D) has important regulatory functions for innate immunity and has been implicated as a biomarker for chronic obstructive pulmonary disease (COPD). We hypothesized that COPD patients ...

    Authors: Jayaji M Moré, Dennis R Voelker, Lori J Silveira, Michael G Edwards, Edward D Chan and Russell P Bowler
    Citation: BMC Pulmonary Medicine 2010 10:53
    Content type: Research article Published on:

  6. The ability to objectively differentiate exacerbations of chronic obstructive pulmonary disease (COPD) from day-to-day symptom variations would be an important development in clinical practice and research. We...

    Authors: John R Hurst, Gavin C Donaldson, Jennifer K Quint, James JP Goldring, Anant RC Patel and Jadwiga A Wedzicha
    Citation: BMC Pulmonary Medicine 2010 10:52
    Content type: Research article Published on:

  7. A significant genetic component has been described for idiopathic pulmonary fibrosis (IPF). The R131H (rs1801274) polymorphism of the IgG receptor FcγRIIa determines receptor affinity for IgG subclasses and is...

    Authors: Stylianos Bournazos, Jacob Grinfeld, Karen M Alexander, John T Murchison, William A Wallace, Pauline McFarlane, Nikhil Hirani, A John Simpson, Ian Dransfield and Simon P Hart
    Citation: BMC Pulmonary Medicine 2010 10:51
    Content type: Research article Published on:

  8. International guidelines recommend long-acting bronchodilators in patients who remain symptomatic despite adequate treatment with short-acting bronchodilators. The purpose of this study is to estimate the effe...

    Authors: Ann Van den Bruel, Jeannine Gailly and Mattias Neyt
    Citation: BMC Pulmonary Medicine 2010 10:50
    Content type: Research article Published on:

  9. Gastro-oesophageal reflux disease (GORD) symptoms are common in asthma and have been extensively studied, but less so in the Asian continent. Reflux-associated respiratory symptoms (RARS) have, in contrast, be...

    Authors: Lakmali D Amarasiri, Arunasalam Pathmeswaran, H Janaka de Silva and Channa D Ranasinha
    Citation: BMC Pulmonary Medicine 2010 10:49
    Content type: Research article Published on:

  11. Tiotropium is reimbursed since March 2004 in Belgium for the treatment of Chronic Obstructive Pulmonary Disease (COPD). Questions however remain on this product's value for money. The purpose of this study is ...

    Authors: Mattias Neyt, Stephan Devriese, Nancy Thiry and Ann Van den Bruel
    Citation: BMC Pulmonary Medicine 2010 10:47
    Content type: Research article Published on:

  12. As more patients with cystic fibrosis (CF) reach adulthood and participate in age-appropriate activities (e.g. employment, dating), disclosure of medical status becomes more important. This study assessed rate...

    Authors: Avani C Modi, Alexandra L Quittner and Michael P Boyle
    Citation: BMC Pulmonary Medicine 2010 10:46
    Content type: Research article Published on:

  13. Pneumonia, and particularly nosocomial (NP) and ventilator-associated pneumonias (VAP), results in high morbidity and costs. NPs in particular are likely to be caused by Pseudomonas aeruginosa (PA), ~20% of which...

    Authors: Marya D Zilberberg, Joyce Chen, Samir H Mody, Andrew M Ramsey and Andrew F Shorr
    Citation: BMC Pulmonary Medicine 2010 10:45
    Content type: Research article Published on:

  14. Chlamydia pneumoniae (C pn) infection causes an acute inflammation in the respiratory system that may become persistent, but little is known about the long-term respiratory effects of C pn infections. Aim: To es...

    Authors: Thorarinn Gislason, Vilmundur Guðnason, Bryndis Benediktsdottir, Isleifur Olafsson, Thor Aspelund, Bjarni Thjodleifsson and Christer Janson
    Citation: BMC Pulmonary Medicine 2010 10:44
    Content type: Research article Published on:

  15. Asthma in children is an emerging public health problem in South America. So far, research in this part of the world is limited. This paper presents the methodology and description of the data acquisition of a...

    Authors: Anja Boneberger, Katja Radon, Jennifer Baer, Leonie Kausel, Michael Kabesch, Daniel Haider, Rudolf Schierl, Rüdiger von Kries and Mario Calvo
    Citation: BMC Pulmonary Medicine 2010 10:43
    Content type: Study protocol Published on:

  16. We assessed the relationship between physiologic parameters, computed tomography patterns, 6 minute walk distance (6MWD) and the distance-saturation product [DSP; defined as the product of the 6MWD and the low...

    Authors: Esam H Alhamad, Shaffi Ahmad Shaik, Majdy M Idrees, Mohammed O Alanezi and Arthur C Isnani
    Citation: BMC Pulmonary Medicine 2010 10:42
    Content type: Research article Published on:

  17. Despite optimal pharmacological therapy and pulmonary rehabilitation, patients with COPD continue to be breathless. There is a need to develop additional strategies to alleviate symptoms. Learning to sing requ...

    Authors: Victoria M Lord, Phoene Cave, Victoria J Hume, Elizabeth J Flude, Amanda Evans, Julia L Kelly, Michael I Polkey and Nicholas S Hopkinson
    Citation: BMC Pulmonary Medicine 2010 10:41
    Content type: Research article Published on:

  18. Proteolysis of matrix components, in particular elastin, is a major contributing factor to the development of lung diseases such as emphysema and chronic obstructive pulmonary disease (COPD). MMP-12 (macrophag...

    Authors: Peter LaPan, Jeff Brady, Christal Grierson, Margaret Fleming, Doug Miller, Joe Sypek and Bin Fu
    Citation: BMC Pulmonary Medicine 2010 10:40
    Content type: Technical advance Published on:

  19. Clinical and experimental data suggest that the inflammatory response is impaired in diabetics and can be modulated by insulin. The present study was undertaken to investigate the role of insulin on the early ...

    Authors: Joilson O Martins, Carlos AL Campos, José WMC Cruz, Simone Manzolli, Venâncio AF Alves, Elcio O Vianna, Sonia Jancar and Paulina Sannomiya
    Citation: BMC Pulmonary Medicine 2010 10:39
    Content type: Research article Published on:

  20. Inadequate glucose control may be simultaneously associated with inflammation and decreased lung function in type 2 diabetes. We evaluated if lung function is worse in patients with inadequate glucose control,...

    Authors: Rodolfo J Dennis, Dario Maldonado, Maria X Rojas, Pablo Aschner, Martin Rondón, Laura Charry and Alejandro Casas
    Citation: BMC Pulmonary Medicine 2010 10:38
    Content type: Research article Published on:

  21. Bronchial Hyperresponsiveness (BHR) is considered a hallmark of asthma. Other methods are helpful in epidemiological respiratory health studies including Fractional Exhaled Nitric Oxide (FENO) and Eosinophils ...

    Authors: Valérie Demange, Pascal Wild, Denis Zmirou-Navier, Paul Tossa, Abraham Bohadana, Annick Barbaud and Christophe Paris
    Citation: BMC Pulmonary Medicine 2010 10:37
    Content type: Research article Published on:

  22. The Eosinophil Cationic Protein (ECP) is a potent multifunctional protein. Three common polymorphisms are present in the ECP gene, which determine the function and production of the protein. The aim was to stu...

    Authors: Ulla-Britt Jönsson, Lena Douhan Håkansson, Rain Jõgi, Christer Janson and Per Venge
    Citation: BMC Pulmonary Medicine 2010 10:36
    Content type: Research article Published on:

  23. Chronic obstructive pulmonary disease (COPD) affects independence and survival in the general population, but it is unknown to which extent this conclusion applies to elderly people with mild disease. The aim ...

    Authors: Claudio Pedone, Simone Scarlata, Claudio Sorino, Francesco Forastiere, Vincenzo Bellia and Raffaele Antonelli Incalzi
    Citation: BMC Pulmonary Medicine 2010 10:35
    Content type: Research article Published on:

  24. Aspirin-intolerant asthma (AIA), which is caused by non-steroidal anti-inflammatory drugs (NSAIDs) such as aspirin, causes lung inflammation and reversal bronchi reduction, leading to difficulty in breathing. ...

    Authors: Jason Yongha Kim, Jeong Hyun Kim, Tae Joon Park, Joon Seol Bae, Jin Sol Lee, Charisse Flerida Pasaje, Byung Lae Park, Hyun Sub Cheong, Jong-Sook Park, Sung-Woo Park, Soo-Taek Uh, Mi-Kyeong Kim, Inseon S Choi, Sang Heon Cho, Byoung Whui Choi, Choon-Sik Park…
    Citation: BMC Pulmonary Medicine 2010 10:34
    Content type: Research article Published on:

  25. Chronic obstructive pulmonary disease (COPD) and a high body mass index (BMI) can both affect pulmonary volumes as well as exercise tolerance, but their combined effect on these outcomes is not well known. The...

    Authors: Louis Laviolette, Francesco Sava, Denis E O'Donnell, Katherine A Webb, Alan L Hamilton, Steven Kesten and François Maltais
    Citation: BMC Pulmonary Medicine 2010 10:33
    Content type: Research article Published on:

  26. Exertional dyspnea is the most prominent and disabling feature in idiopathic pulmonary fibrosis (IPF). The Medical Research Chronic (MRC) chronic dyspnea score as well as physiological measurements obtained du...

    Authors: Effrosyni D Manali, Panagiotis Lyberopoulos, Christina Triantafillidou, Likourgos F Kolilekas, Christina Sotiropoulou, Joseph Milic-Emili, Charis Roussos and Spyros A Papiris
    Citation: BMC Pulmonary Medicine 2010 10:32
    Content type: Research article Published on:

  27. Both Peak Oxygen Uptake (peak VO2), from cardiopulmonary exercise testing (CPET) and the distance walked during a Six-Minute Walk Test (6 MWD) are used for following the natural history of various diseases, ti...

    Authors: Robert M Ross, Jayasimha N Murthy, Istvan D Wollak and Andrew S Jackson
    Citation: BMC Pulmonary Medicine 2010 10:31
    Content type: Research article Published on:

  28. Airway epithelial cells are critical in host defense against bacteria including Mycoplasma pneumoniae (Mp) in chronic obstructive pulmonary disease (COPD) and asthma. β2-agonists are mainstay of COPD and asthma t...

    Authors: Claire A Gross, Russell P Bowler, Rebecca M Green, Andrew R Weinberger, Christina Schnell and Hong Wei Chu
    Citation: BMC Pulmonary Medicine 2010 10:30
    Content type: Research article Published on:

  29. Asthma management guidelines recommend a stepwise approach to instituting and adjusting anti-inflammatory controller therapy for children with asthma. The objective of this retrospective observational study wa...

    Authors: Mike Thomas, Tarita Murray-Thomas, Tao Fan, Tim Williams and Stephanie Taylor
    Citation: BMC Pulmonary Medicine 2010 10:29
    Content type: Research article Published on:

  30. In chronic obstructive pulmonary disease (COPD), the response of the forced expiratory volume in 1 second (FEV1) after bronchodilator application is weak. Inspiratory parameters like the forced inspiratory vol...

    Authors: Frank J Visser, Sunil Ramlal, Ben Pelzer, PN Richard Dekhuijzen and Yvonne F Heijdra
    Citation: BMC Pulmonary Medicine 2010 10:28
    Content type: Research article Published on:

  31. Injection drug use is associated with an increased risk of human immunodeficiency virus (HIV) infection and with obstructive lung diseases (OLD). Understanding how HIV and OLD may impact respiratory symptoms a...

    Authors: M Bradley Drummond, Gregory D Kirk, Erin P Ricketts, Meredith C McCormack, J Christian Hague, John F McDyer, Shruti H Mehta, Eric A Engels, Robert A Wise and Christian A Merlo
    Citation: BMC Pulmonary Medicine 2010 10:27
    Content type: Research article Published on:

  32. Pulmonary fibrosis (PF) is a group of devastating and largely irreversible diseases. Phosphodiesterase (PDE) 4 is involved in the processes of remodeling and inflammation, which play key role in tissue fibrosi...

    Authors: Sergey Udalov, Rio Dumitrascu, Soni S Pullamsetti, Hamza M Al-tamari, Norbert Weissmann, Hossein A Ghofrani, Andreas Guenther, Robert Voswinckel, Werner Seeger, Friedrich Grimminger and Ralph T Schermuly
    Citation: BMC Pulmonary Medicine 2010 10:26
    Content type: Research article Published on:

    The Correction to this article has been published in BMC Pulmonary Medicine 2022 22:113

  33. Ventilator-induced lung injury (VILI) is a recognized complication of mechanical ventilation. Although the specific mechanism by which mechanical ventilation causes lung injury remains an active area of study,...

    Authors: Scott E Sinclair, Nayak L Polissar and William A Altemeier
    Citation: BMC Pulmonary Medicine 2010 10:25
    Content type: Research article Published on:

  34. The aim is to assess the validity and reliability of transbronchial needle aspiration (TBNA) of mediastinal and hilar adenopathies and to evaluate factors predictive of TBNA outcome.

    Authors: Alberto Fernández-Villar, Maribel Botana, Virginia Leiro, Ana González, Cristina Represas and Alberto Ruano-Raviña
    Citation: BMC Pulmonary Medicine 2010 10:24
    Content type: Research article Published on:

  35. 8-Isoprostane (8-IP) is a marker of lipid peroxidation. Elevated concentrations have been reported in BAL fluid and exhaled breath condensate (EBC) in sarcoidosis (S). To validate the prognostic value of this ...

    Authors: Wojciech J Piotrowski, Zofia Kurmanowska, Adam Antczak, Jerzy Marczak and Paweł Górski
    Citation: BMC Pulmonary Medicine 2010 10:23
    Content type: Research article Published on:

  36. Liver dysfunction reflects the status of heart failure, with congestion and low perfusion of the liver serving as causative mechanisms. Previous studies demonstrated relationship between the results of liver f...

    Authors: Yasuko Takeda, Yutaka Takeda, Shigehiro Tomimoto, Tomomitsu Tani, Hitomi Narita and Genjiro Kimura
    Citation: BMC Pulmonary Medicine 2010 10:22
    Content type: Research article Published on:

  37. A large number of studies have investigated the effects of high tidal volume ventilation in mouse models. In contrast data on very short term effects of low tidal volume ventilation are sparse. Therefore we in...

    Authors: Hans P Hauber, Dörte Karp, Torsten Goldmann, Ekkehard Vollmer and Peter Zabel
    Citation: BMC Pulmonary Medicine 2010 10:21
    Content type: Research article Published on:

    The Erratum to this article has been published in BMC Pulmonary Medicine 2012 12:7

  38. While lipopolysaccharide (LPS) from Gram-negative bacteria has been shown to augment inflammation in ventilated lungs information on the effect of Gram-positive bacteria is lacking. Therefore the effect of LPS...

    Authors: Hans P Hauber, Dörte Karp, Torsten Goldmann, Ekkehard Vollmer and Peter Zabel
    Citation: BMC Pulmonary Medicine 2010 10:20
    Content type: Research article Published on:

  39. Few studies have been carried out on acute effects of cement dust exposure. This study is conducted to investigate the associations between current "total" dust exposure and acute respiratory symptoms and resp...

    Authors: Zeyede K Zeleke, Bente E Moen and Magne Bråtveit
    Citation: BMC Pulmonary Medicine 2010 10:19
    Content type: Research article Published on:

  40. Right ventricular dilatation in the setting of acute pulmonary embolism is associated with an adverse prognosis. Treatment with a pulmonary vasodilator has never been studied systematically. We evaluated the e...

    Authors: Albertus J Kooter, Richard G IJzerman, Otto Kamp, Anco B Boonstra and Yvo M Smulders
    Citation: BMC Pulmonary Medicine 2010 10:18
    Content type: Research article Published on:

  41. Pulsus paradoxus estimated by dynamic change in area under the oximeter plethysmograph waveform (PEP) might provide a measure of acute asthma severity. Our primary objective was to determine how well PEP corre...

    Authors: Donald H Arnold, Cathy A Jenkins and Tina V Hartert
    Citation: BMC Pulmonary Medicine 2010 10:17
    Content type: Research article Published on:

  42. Obesity and asthma have reached epidemic proportions in the US. Their concurrent rise over the last 30 years suggests that they may be connected. Numerous observational studies support a temporally-correct, do...

    Authors: Jun Ma, Peg Strub, Carlos A Camargo Jr, Lan Xiao, Estela Ayala, Christopher D Gardner, A Sonia Buist, William L Haskell, Phillip W Lavori and Sandra R Wilson
    Citation: BMC Pulmonary Medicine 2010 10:16
    Content type: Study protocol Published on:

  43. The prevalence of anemia in the intensive care unit is well-described. Less is known, however, of the prevalence of anemia in hospitalized patients with lesser illness severity or without organ dysfunction. Co...

    Authors: Michael C Reade, Lisa Weissfeld, Derek C Angus, John A Kellum and Eric B Milbrandt
    Citation: BMC Pulmonary Medicine 2010 10:15
    Content type: Research article Published on:

  44. There is much interest in the possibility that perinatal factors may influence the risk of disease in later life. We investigated the influence of maternal and perinatal factors on subsequent hospital admissio...

    Authors: Rebekah Davidson, Stephen E Roberts, Clare J Wotton and Michael J Goldacre
    Citation: BMC Pulmonary Medicine 2010 10:14
    Content type: Research article Published on:

  45. Smoking cessation is the best possible way to prevent the progression of smoking related airway diseases. However, the effect and time scale of smoking cessation on airway inflammation/remodelling are largely ...

    Authors: Noora Louhelainen, Harri Stark, Witold Mazur, Paula Rytilä, Ratko Djukanovic and Vuokko L Kinnula
    Citation: BMC Pulmonary Medicine 2010 10:13
    Content type: Research article Published on:

  46. Despite recommendations for outpatient management, low risk patients with lower respiratory tract infections (LRTIs) are often hospitalized. This survey analyzed perceptions of physicians, nurses, patients and...

    Authors: Claudia Baehni, Sabine Meier, Pamela Spreiter, Ursula Schild, Katharina Regez, Rita Bossart, Robert Thomann, Claudine Falconnier, Mirjam Christ-Crain, Sabina De Geest, Beat Müller and Philipp Schuetz
    Citation: BMC Pulmonary Medicine 2010 10:12
    Content type: Research article Published on:

  47. Indacaterol is a novel, once-daily (o.d.) inhaled, long-acting β 2-agonist in development for chronic obstructive pulmonary disease (COPD). This 12-week, double-blind study compared the efficacy, safety, and tole...

    Authors: Gregory Feldman, Thomas Siler, Niyati Prasad, Damon Jack, Simon Piggott, Roger Owen, Mark Higgins and Benjamin Kramer
    Citation: BMC Pulmonary Medicine 2010 10:11
    Content type: Research article Published on:

  48. Health status, dyspnea and psychological status are important clinical outcomes in chronic obstructive pulmonary disease (COPD). However, forced expiratory volume in one second (FEV1) measured by spirometry, the ...

    Authors: Akane Haruna, Toru Oga, Shigeo Muro, Tadashi Ohara, Susumu Sato, Satoshi Marumo, Daisuke Kinose, Kunihiko Terada, Michiyoshi Nishioka, Emiko Ogawa, Yuma Hoshino, Toyohiro Hirai, Kazuo Chin and Michiaki Mishima
    Citation: BMC Pulmonary Medicine 2010 10:10
    Content type: Research article Published on:

  49. Heart failure (HF) and sleep apnoea (SA) association has been recognized but whether it results from confounding factors (hypertension, ischaemia, obesity) remains unclear.

    Authors: Susana Ferreira, Anabela Marinho, Marta Patacho, Elisabete Santa-Clara, Cristina Carrondo, João Winck and Paulo Bettencourt
    Citation: BMC Pulmonary Medicine 2010 10:9
    Content type: Research article Published on:

  50. Pandemic Influenza A (H1N1) 2009 is a novel viral infection that emerged in March 2009. This is the first report addressing the clinical course of patients with cystic fibrosis (CF) and H1N1 infection.

    Authors: Megan W France, Szeanna Tai, Phillip J Masel, Vanessa L Moore, Tracy L McMahon, Alexander J Ritchie and Scott C Bell
    Citation: BMC Pulmonary Medicine 2010 10:8
    Content type: Research article Published on:
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BMC Pulmonary Medicine

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