Genetic influences on right ventricular systolic pressure (RVSP) in chronic obstructive pulmonary disease (COPD)

BMC Pulmonary Medicine

Table 4 Association of genotype groups with FEV ₁ % predicted, using ANOVA

Gene	Genotypes	Number	Mean FEV₁% predicted	Standard Deviation	Pvalue
VEGFA	GG	246	48.7	21.0	0.23
	GC	256	50.6	22.7
	CC	75	53.5	20.4
		Total 577		21.7
NOS3-VNTR	4bb	414	50.0	22.3	0.80
	4ab	148	51.0	20.6
	4aa	15	47.7	17.7
		Total 577		21.7
ACE	II	142	49.6	20.9	0.09
	ID	283	48.8	21.9
	DD	153	53.6	22.2
		Total 578		21.8
SLC6A4	LL	179	49.7	22.7	0.97
	LS	285	50.2	21.2
	SS	107	50.2	22.1
		Total 571		21.8
PTGIS	CC	336	50.0	21.0	0.77
	CA	200	49.9	22.8
	AA	42	52.4	23.1
		Total 578		21.7
NOS3-298	GG	258	50.1	21.0	0.61
	GT	276	50.9	22.8
	TT	41	47.4	18.3
		Total 575		21.7
EDN1	GG	322	50.0	22.4	0.77
	GT	178	50.6	21.3
	TT	42	47.9	19.1
		Total 542		21.8

ISSN: 1471-2466