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Fig. 1 | BMC Pulmonary Medicine

Fig. 1

From: Mycobacteria infect different cell types in the human lung and cause species dependent cellular changes in infected cells

Fig. 1

Results of the TUNEL assays. PC = Positive Control (fresh lung preparations without ex vivo cultivation, N = 17), ev: Mean of all different ex vivo cultivated lung specimens, including Medium control (MED, N = 12), lungs infected with M. abscessus (AB, N = 17), M. avium (AV, N = 7) and M. tuberculosis (TB, N = 18). NC = Negative Controls (treated by DNase I, N = 8). Left panel: No significant increase of DNA-double strand breaks upon tissue culture. Right panel: Differences between the respective mycobacterial species. These results related with multiple factors analyzed by a factorial ANOVA [2×6 factorial design: subject factors were cell type (1-alive and 2-apoptotic cells) and groups (1-PC, 2-MED, 3-AB, 4-AV, 5-TB, 6-NC)]

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BMC Pulmonary Medicine

ISSN: 1471-2466

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