Organization WH: Global Tuberculosis Report 2014. World Health Organization; 2015.
Griffith DE, Aksamit T, Brown-Elliott BA, Catanzaro A, Daley C, Gordin F, et al. An official ATS/IDSA statement: diagnosis, treatment, and prevention of nontuberculous mycobacterial diseases. Am J Respir Crit Care Med. 2007;175:367–416.
Article
CAS
PubMed
Google Scholar
van Ingen J, Bendien SA, de Lange WC, Hoefsloot W, Dekhuijzen PN, Boeree MJ, et al. Clinical relevance of non-tuberculous mycobacteria isolated in the Nijmegen-Arnhem region, The Netherlands. Thorax. 2009;64:502–6.
Article
PubMed
Google Scholar
Gupta UD, Katoch VM. Animal models of tuberculosis. Tuberculosis (Edinb). 2005;85:277–93.
Article
CAS
Google Scholar
Ulrichs T, Kaufmann SH. Mycobacterial persistence and immunity. Front Biosci. 2002;7:d458–69.
Article
CAS
PubMed
Google Scholar
Shen Y, Zhou D, Qiu L, Lai X, Simon M, Shen L, et al. Adaptive immune response of Vgamma2Vdelta2+ T cells during mycobacterial infections. Science. 2002;295:2255–8.
Article
PubMed Central
CAS
PubMed
Google Scholar
Shi L, Ryan GJ, Bhamidi S, Troudt J, Amin A, Izzo A, et al. Isolation and purification of Mycobacterium tuberculosis from H37Rv infected guinea pig lungs. Tuberculosis (Edinb). 2014;94:525–30.
Article
CAS
Google Scholar
Flynn JL. Lessons from experimental Mycobacterium tuberculosis infections. Microbes Infect. 2006;8:1179–88.
Article
CAS
PubMed
Google Scholar
Actor J, Hunter Jr R, Jagannath C. Immunopathology of Tuberculosis. In: Zander D, Popper H, Jagirdar J, Haque A, Cagle P, Barrios R, editors. Molecular Pathology of Lung Diseases. Volume 1. New York: Springer New York; 2008. p. 419–28. Molecular Pathology Library.
Chapter
Google Scholar
Rivero-Lezcano OM. In vitro infection of human cells with Mycobacterium tuberculosis. Tuberculosis (Edinb). 2013;93:123–9.
Article
CAS
Google Scholar
Danelishvili L, McGarvey J, Li YJ, Bermudez LE. Mycobacterium tuberculosis infection causes different levels of apoptosis and necrosis in human macrophages and alveolar epithelial cells. Cell Microbiol. 2003;5:649–60.
Article
CAS
PubMed
Google Scholar
Lee J, Remold HG, Leong MH, Kornfeld H. Macrophage apoptosis in response to high intracellular burden of Mycobacterium tuberculosis is mediated by a novel caspase-independent pathway. J Immunol. 2006;176:4267–74.
Article
CAS
PubMed
Google Scholar
Crowle AJ, May M. Preliminary demonstration of human tuberculoimmunity in vitro. Infect Immun. 1981;31:453–64.
PubMed Central
CAS
PubMed
Google Scholar
Steele J, Flint KC, Pozniak AL, Hudspith B, Johnson MM, Rook GA. Inhibition of virulent Mycobacterium tuberculosis by murine peritoneal macrophages and human alveolar lavage cells: the effects of lymphokines and recombinant gamma interferon. Tubercle. 1986;67:289–94.
Article
CAS
PubMed
Google Scholar
Brown AE, Holzer TJ, Andersen BR. Capacity of human neutrophils to kill Mycobacterium tuberculosis. J Infect Dis. 1987;156:985–9.
Article
CAS
PubMed
Google Scholar
Peterson PK, Gekker G, Hu S, Sheng WS, Anderson WR, Ulevitch RJ, et al. CD14 receptor-mediated uptake of nonopsonized Mycobacterium tuberculosis by human microglia. Infect Immun. 1995;63:1598–602.
PubMed Central
CAS
PubMed
Google Scholar
Stokes RW, Doxsee D. The receptor-mediated uptake, survival, replication, and drug sensitivity of Mycobacterium tuberculosis within the macrophage-like cell line THP-1: a comparison with human monocyte-derived macrophages. Cell Immunol. 1999;197:1–9.
Article
CAS
PubMed
Google Scholar
Rockett KA, Brookes R, Udalova I, Vidal V, Hill AV, Kwiatkowski D. 1,25-Dihydroxyvitamin D3 induces nitric oxide synthase and suppresses growth of Mycobacterium tuberculosis in a human macrophage-like cell line. Infect Immun. 1998;66:5314–21.
PubMed Central
CAS
PubMed
Google Scholar
Caccamo N, Milano S, Di Sano C, Cigna D, Ivanyi J, Krensky AM, et al. Identification of epitopes of Mycobacterium tuberculosis 16-kDa protein recognized by human leukocyte antigen-A*0201 CD8(+) T lymphocytes. J Infect Dis. 2002;186:991–8.
Article
CAS
PubMed
Google Scholar
Shepard CC. Growth characteristics of tubercle bacilli and certain other mycobacteria in HeLa cells. J Exp Med. 1957;105:39–48.
Article
PubMed Central
CAS
PubMed
Google Scholar
Bermudez LE, Goodman J. Mycobacterium tuberculosis invades and replicates within type II alveolar cells. Infect Immun. 1996;64:1400–6.
PubMed Central
CAS
PubMed
Google Scholar
Mackaness GB. The growth of tubercle bacilli in monocytes from normal and vaccinated rabbits. Am Rev Tuberc. 1954;69:495–504.
CAS
PubMed
Google Scholar
Suter E. The multiplication of tubercle bacilli within normal phagocytes in tissue culture. J Exp Med. 1952;96:137–50.
Article
PubMed Central
CAS
PubMed
Google Scholar
Patterson RJ, Youmans GP. Multiplication of Mycobacterium tuberculosis Within Normal and “Immune” Mouse Macrophages Cultivated With and Without Streptomycin. Infect Immun. 1970;1:30–40.
PubMed Central
CAS
PubMed
Google Scholar
Lamhamedi-Cherradi S, de Chastellier C, Casanova JL. Growth of Mycobacterium bovis, Bacille Calmette-Guerin, within human monocytes-macrophages cultured in serum-free medium. J Immunol Methods. 1999;225:75–86.
Article
CAS
PubMed
Google Scholar
Ernst JD. Macrophage receptors for Mycobacterium tuberculosis. Infect Immun. 1998;66:1277–81.
PubMed Central
CAS
PubMed
Google Scholar
Wallis RS, Vinhas S, Janulionis E. Strain specificity of antimycobacterial immunity in whole blood culture after cure of tuberculosis. Tuberculosis (Edinb). 2009;89:221–4.
Article
Google Scholar
Bermudez LE, Sangari FJ, Kolonoski P, Petrofsky M, Goodman J. The efficiency of the translocation of Mycobacterium tuberculosis across a bilayer of epithelial and endothelial cells as a model of the alveolar wall is a consequence of transport within mononuclear phagocytes and invasion of alveolar epithelial cells. Infect Immun. 2002;70:140–6.
Article
PubMed Central
CAS
PubMed
Google Scholar
Bonay M, Bouchonnet F, Pelicic V, Lagier B, Grandsaigne M, Lecossier D, et al. Effect of stimulation of human macrophages on intracellular survival of Mycobacterium bovis Bacillus Calmette-Guerin. Evaluation with a mycobacterial reporter strain. Am J Respir Crit Care Med. 1999;159:1629–37.
Article
CAS
PubMed
Google Scholar
Martineau AR, Wilkinson KA, Newton SM, Floto RA, Norman AW, Skolimowska K, et al. IFN-gamma- and TNF-independent vitamin D-inducible human suppression of mycobacteria: the role of cathelicidin LL-37. J Immunol. 2007;178:7190–8.
Article
CAS
PubMed
Google Scholar
Garg SK, Volpe E, Palmieri G, Mattei M, Galati D, Martino A, et al. Sphingosine 1-phosphate induces antimicrobial activity both in vitro and in vivo. J Infect Dis. 2004;189:2129–38.
Article
CAS
PubMed
Google Scholar
Kusner DJ, Adams J. ATP-induced killing of virulent Mycobacterium tuberculosis within human macrophages requires phospholipase D. J Immunol. 2000;164:379–88.
Article
CAS
PubMed
Google Scholar
Morrison J, Pai M, Hopewell PC. Tuberculosis and latent tuberculosis infection in close contacts of people with pulmonary tuberculosis in low-income and middle-income countries: a systematic review and meta-analysis. Lancet Infect Dis. 2008;8:359–68.
Article
PubMed
Google Scholar
Jager J, Marwitz S, Tiefenau J, Rasch J, Shevchuk O, Kugler C, et al. Human lung tissue explants reveal novel interactions during Legionella pneumophila infections. Infect Immun. 2014;82:275–85.
Article
PubMed Central
PubMed
Google Scholar
Harrison F, Muruli A, Higgins S, Diggle SP. Development of an ex vivo porcine lung model for studying growth, virulence, and signaling of Pseudomonas aeruginosa. Infect Immun. 2014;82:3312–23.
Article
PubMed Central
PubMed
Google Scholar
Szymanski KV, Toennies M, Becher A, Fatykhova D, N’Guessan PD, Gutbier B, et al. Streptococcus pneumoniae-induced regulation of cyclooxygenase-2 in human lung tissue. Eur Respir J. 2012;40:1458–67.
Article
CAS
PubMed
Google Scholar
Rupp J, Droemann D, Goldmann T, Zabel P, Solbach W, Vollmer E, et al. Alveolar epithelial cells type II are major target cells for C. pneumoniae in chronic but not in acute respiratory infection. FEMS Immunol Med Microbiol. 2004;41:197–203.
Article
CAS
PubMed
Google Scholar
Droemann D, Rupp J, Rohmann K, Osbahr S, Ulmer AJ, Marwitz S, et al. The TGF-beta-pseudoreceptor BAMBI is strongly expressed in COPD lungs and regulated by nontypeable Haemophilus influenzae. Respir Res. 2010;11:67.
Article
Google Scholar
Shevchuk O, Abidi N, Klawonn F, Wissing J, Nimtz M, Kugler C, et al. HOPE-Fixation of Lung Tissue Allows Retrospective Proteome and Phosphoproteome Studies. J Proteome Res. 2014;13:5230–9.
Article
CAS
PubMed
Google Scholar
Olert J, Wiedorn KH, Goldmann T, Kuhl H, Mehraein Y, Scherthan H, et al. HOPE fixation: a novel fixing method and paraffin-embedding technique for human soft tissues. Pathol Res Pract. 2001;197:823–6.
Article
CAS
PubMed
Google Scholar
Fellenberg K, Hauser NC, Brors B, Neutzner A, Hoheisel JD, Vingron M. Correspondence analysis applied to microarray data. Proc Natl Acad Sci U S A. 2001;98:10781–6.
Article
PubMed Central
CAS
PubMed
Google Scholar
Lang DS, Droemann D, Schultz H, Branscheid D, Martin C, Ressmeyer AR, et al. A novel human ex vivo model for the analysis of molecular events during lung cancer chemotherapy. Respir Res. 2007;8:43.
Article
PubMed Central
PubMed
Google Scholar
Xu F, Droemann D, Rupp J, Shen H, Wu X, Goldmann T, et al. Modulation of the inflammatory response to Streptococcus pneumoniae in a model of acute lung tissue infection. Am J Respir Cell Mol Biol. 2008;39:522–9.
Article
CAS
PubMed
Google Scholar
Organization WH: Global Tuberculosis Report 2013. World Health Organization; 2014
O’Garra A, Redford PS, McNab FW, Bloom CI, Wilkinson RJ, Berry MP. The immune response in tuberculosis. Annu Rev Immunol. 2013;31:475–527.
Article
PubMed
Google Scholar
Jereb J, Etkind SC, Joglar OT, Moore M, Taylor Z. Tuberculosis contact investigations: outcomes in selected areas of the United States, 1999. Int J Tuberc Lung Dis. 2003;7:S384–90.
CAS
PubMed
Google Scholar
Marks SM, Taylor Z, Qualls NL, Shrestha-Kuwahara RJ, Wilce MA, Nguyen CH. Outcomes of contact investigations of infectious tuberculosis patients. Am J Respir Crit Care Med. 2000;162:2033–8.
Article
CAS
PubMed
Google Scholar
Styblo K. Recent advances in epidemiological research in tuberculosis. Adv Tuberc Res. 1980;20:1–63.
CAS
PubMed
Google Scholar
Vinay Kumar AKA, Fausto N, Aster J. Robbins and Cotran: Pathologic Basis of Disease. 8th ed. 2010.
Google Scholar
Robert J. Mason VCB, Thomas Martin, Talmadge E King, Jr., Schraufnagel, John F. Murray, FRCP, Jay A. Nadel, Jay A. Nadel, : Murray and Nadel’s Textbook of Respiratory Medicine. Saunders; 2010.
Ryan K, Ray CG, Ahmad N, Drew WL, Plorde J. Sherris Medical Microbiology. McGraw-Hill Education: Fifth Edition; 2009.
Google Scholar
Agdestein A, Jones A, Flatberg A, Johansen TB, Heffernan IA, Djonne B, et al. Intracellular growth of Mycobacterium avium subspecies and global transcriptional responses in human macrophages after infection. BMC Genomics. 2014;15:58.
Article
PubMed Central
PubMed
Google Scholar
Lee J, Hartman M, Kornfeld H. Macrophage apoptosis in tuberculosis. Yonsei Med J. 2009;50:1–11.
Article
PubMed Central
PubMed
Google Scholar
Keane J, Remold HG, Kornfeld H. Virulent Mycobacterium tuberculosis strains evade apoptosis of infected alveolar macrophages. J Immunol. 2000;164:2016–20.
Article
CAS
PubMed
Google Scholar
Wallis RS, Amir-Tahmasseb M, Ellner JJ. Induction of interleukin 1 and tumor necrosis factor by mycobacterial proteins: the monocyte western blot. Proc Natl Acad Sci U S A. 1990;87:3348–52.
Article
PubMed Central
CAS
PubMed
Google Scholar
Zhang Y, Doerfler M, Lee TC, Guillemin B, Rom WN. Mechanisms of stimulation of interleukin-1 beta and tumor necrosis factor-alpha by Mycobacterium tuberculosis components. J Clin Invest. 1993;91:2076–83.
Article
PubMed Central
CAS
PubMed
Google Scholar
Fulton SA, Cross JV, Toossi ZT, Boom WH. Regulation of interleukin-12 by interleukin-10, transforming growth factor-beta, tumor necrosis factor-alpha, and interferon-gamma in human monocytes infected with Mycobacterium tuberculosis H37Ra. J Infect Dis. 1998;178:1105–14.
Article
CAS
PubMed
Google Scholar
Friedland JS, Remick DG, Shattock R, Griffin GE. Secretion of interleukin-8 following phagocytosis of Mycobacterium tuberculosis by human monocyte cell lines. Eur J Immunol. 1992;22:1373–8.
Article
CAS
PubMed
Google Scholar
Shaw TC, Thomas LH, Friedland JS. Regulation of IL-10 secretion after phagocytosis of Mycobacterium tuberculosis by human monocytic cells. Cytokine. 2000;12:483–6.
Article
CAS
PubMed
Google Scholar
Gilloteaux J, Jamison JM, Arnold D, Summers JL. Autoschizis: another cell death for cancer cells induced by oxidative stress. Ital J Anat Embryol. 2001;106:79–92.
CAS
PubMed
Google Scholar
Gilloteaux J, Jamison JM, Arnold D, Ervin E, Eckroat L, Docherty JJ, et al. Cancer cell necrosis by autoschizis: synergism of antitumor activity of vitamin C: vitamin K3 on human bladder carcinoma T24 cells. Scanning. 1998;20:564–75.
Article
CAS
PubMed
Google Scholar
Pais V, Danaila L, Pais E. A comparative ultrastructural study of a new type of autoschizis versus a survival cellular mechanism that involves cell membranes of cerebral arteries in humans. Ultrastruct Pathol. 2012;36:166–70.
Article
PubMed
Google Scholar
Esquivel-Solis H, Vallecillo AJ, Benitez-Guzman A, Adams LG, Lopez-Vidal Y, Gutierrez-Pabello JA. Nitric oxide not apoptosis mediates differential killing of Mycobacterium bovis in bovine macrophages. PLoS One. 2013;8, e63464.
Article
PubMed Central
CAS
PubMed
Google Scholar
Mendoza-Aguilar MD, Arce-Paredes P, Aquino-Vega M, Rodríguez-Martínez S, Rojas-Espinosa O. Fate of Mycobacterium tuberculosis in peroxidase-loaded resting murine macrophages. International Journal of Mycobacteriology. 2013;2:3–13.
Article
PubMed
Google Scholar
Chan J, Xing Y, Magliozzo RS, Bloom BR. Killing of virulent Mycobacterium tuberculosis by reactive nitrogen intermediates produced by activated murine macrophages. J Exp Med. 1992;175:1111–22.
Article
CAS
PubMed
Google Scholar
Wolbers F, Buijtenhuijs P, Haanen C, Vermes I. Apoptotic cell death kinetics in vitro depend on the cell types and the inducers used. Apoptosis. 2004;9:385–92.
Article
CAS
PubMed
Google Scholar
Fox S, Leitch AE, Duffin R, Haslett C, Rossi AG. Neutrophil apoptosis: relevance to the innate immune response and inflammatory disease. J Innate Immun. 2010;2:216–27.
Article
PubMed Central
CAS
PubMed
Google Scholar
McCracken JM, Allen LA. Regulation of human neutrophil apoptosis and lifespan in health and disease. J Cell Death. 2014;7:15–23.
PubMed Central
CAS
PubMed
Google Scholar
Young B, Stewart W, O’Dowd G. Wheater’s Basic Pathology: A Text, Atlas and Review of Histopathology. London: Churchill Livingstone/Elsevier; 2011.
Google Scholar
Summers C, Rankin SM, Condliffe AM, Singh N, Peters AM, Chilvers ER. Neutrophil kinetics in health and disease. Trends Immunol. 2010;31:318–24.
Article
PubMed Central
CAS
PubMed
Google Scholar
Vergne I, Chua J, Singh SB, Deretic V. Cell biology of mycobacterium tuberculosis phagosome. Annu Rev Cell Dev Biol. 2004;20:367–94.
Article
CAS
PubMed
Google Scholar
Bocchino M, Galati D, Sanduzzi A, Colizzi V, Brunetti E, Mancino G. Role of mycobacteria-induced monocyte/macrophage apoptosis in the pathogenesis of human tuberculosis. Int J Tuberc Lung Dis. 2005;9:375–83.
CAS
PubMed
Google Scholar
Yang CT, Cambier CJ, Davis JM, Hall CJ, Crosier PS, Ramakrishnan L. Neutrophils exert protection in the early tuberculous granuloma by oxidative killing of mycobacteria phagocytosed from infected macrophages. Cell Host Microbe. 2012;12:301–12.
Article
PubMed Central
CAS
PubMed
Google Scholar
Bogdan C, Rollinghoff M, Diefenbach A. Reactive oxygen and reactive nitrogen intermediates in innate and specific immunity. Curr Opin Immunol. 2000;12:64–76.
Article
CAS
PubMed
Google Scholar
Winterbourn CC. Reconciling the chemistry and biology of reactive oxygen species. Nat Chem Biol. 2008;4:278–86.
Article
CAS
PubMed
Google Scholar
Jones GS, Amirault HJ, Andersen BR. Killing of Mycobacterium tuberculosis by neutrophils: a nonoxidative process. J Infect Dis. 1990;162:700–4.
Article
CAS
PubMed
Google Scholar
Kisich KO, Higgins M, Diamond G, Heifets L. Tumor necrosis factor alpha stimulates killing of Mycobacterium tuberculosis by human neutrophils. Infect Immun. 2002;70:4591–9.
Article
PubMed Central
CAS
PubMed
Google Scholar
Martineau AR, Newton SM, Wilkinson KA, Kampmann B, Hall BM, Nawroly N, et al. Neutrophil-mediated innate immune resistance to mycobacteria. J Clin Invest. 2007;117:1988–94.
Article
PubMed Central
CAS
PubMed
Google Scholar
Majeed M, Perskvist N, Ernst JD, Orselius K, Stendahl O. Roles of calcium and annexins in phagocytosis and elimination of an attenuated strain of Mycobacterium tuberculosis in human neutrophils. Microb Pathog. 1998;24:309–20.
Article
CAS
PubMed
Google Scholar
Stead WW, Senner JW, Reddick WT, Lofgren JP. Racial differences in susceptibility to infection by Mycobacterium tuberculosis. N Engl J Med. 1990;322:422–7.
Article
CAS
PubMed
Google Scholar