Table 4 Selected studies on the association between Borrelia species and sarcoidosis
First author/Year (Ref.) | Country | Molecular Technique | Sarcoidosis | Controls | OR (95% CI) | ||
|---|---|---|---|---|---|---|---|
n/N | Type of microorganism | n/N | Type of microorganism | ||||
Derler, 2009 [4] | Austria | Focus-floating microscopy and Borrelia-specific PCR DNA | 13/35 | Borrelia sp. | 1/61 | Borrelia sp. | 35.45 (4.38–287.16) |
Ishihara, 1998 [65] | Japan | Dot-blot analysis (Dotblot Borrelia Kit) | 15/46 | Borrelia sp. | 2/100 | Borrelia sp. | 23.71 (5.14–109.46) |
Martens, 1997 [66] | Germany | Western blot for Borrelia burgdorferi | 1/60 | Borrelia burgdorferi | 27/1000 | Borrelia burdorferi | 0.61 (0.08–4.57) |
Lian, 1995 [67] | China | PCR for Borrelia burgdorferi DNA | 6/49 | Borrelia burgdorferi | 2/28 | Borrelia burgdorferi | 1.81 (0.34–9.66) |
Xu, 1996 [68] | China | In situ PCR for Borrelia burgdorferi DNA | 0/23 | - | 0/23 | - | - |
Ishihara, 1996 [69] | Japan | Elisa and Dot-blot analysis for Borrelia sp. | 1/38 | Borrelia sp. | 1/80 | Borrelia sp. | 2.14 (0.13–35.08) |