Skip to main content

Should Aspergillus screening before bronchial thermoplasty?

Peer Review reports

Main text

Thank you for your feedback. If there were any findings suspicious of allergic bronchopulmonary Aspergillosis (ABPA), aspergillus-specific antibody measurements and skin tests would have been performed as screening [1]. However, this case did not show any findings considered to be ABPA such as bronchodilation and mucus plugs on computed tomography (CT) and bronchoscopy before treatment [2]. On the other hand, regarding the sessions of bronchial thermoplasty (BT) for severe asthma, the third session was performed after the sample was collected, so BT treatment was completed. Regarding BT indications, although regular steroid administration was not performed in this case, a single rescue steroid administration was performed, and it is judged to be within the indication in Japan.

The question is, do you order Aspergillus-specific antibodies or skin tests on all cases of asthma that are not abnormal on CT and bronchoscopy?

Availability of data and materials

All data and material are available for sharing if needed.

Abbreviations

ABPA:

Allergic bronchopulmonary Aspergillosis

BT:

Bronchial thermoplasty

CT:

Computed tomography

References

  1. Asano K, Hebisawa A, Ishiguro T, et al. New clinical diagnostic criteria for allergic bronchopulmonary Aspergillosis/mycosis and its validation. J Allergy Clin Immunol. 2021;147:1261-1268.e5. https://doi.org/10.1016/j.jaci.2020.08.029.

    Article  PubMed  Google Scholar 

  2. Sasada S, Ohmura K, Oguri T, et al. A case report of Aspergillosis accompanied by saccular bronchodilation after bronchial thermoplasty in a 19-year-old woman. BMC Pulm Med. 2020;20:312. https://doi.org/10.1186/s12890-020-01352y.

    Article  PubMed  PubMed Central  Google Scholar 

Download references

Funding

No funding sources were used.

Author information

Authors and Affiliations

Authors

Contributions

S. S. significantly contributed to this paper.

Corresponding author

Correspondence to Shinji Sasada.

Ethics declarations

Ethics approval and consent to participate

Not applicable.

Consent to publish

Not applicable.

Competing interests

The authors declare that they have no competing interests.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Sasada, S. Should Aspergillus screening before bronchial thermoplasty?. BMC Pulm Med 21, 195 (2021). https://doi.org/10.1186/s12890-021-01536-0

Download citation

  • Received:

  • Accepted:

  • Published:

  • DOI: https://doi.org/10.1186/s12890-021-01536-0

Keywords