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Table 2 Logistic regression analyses for the diagnosis of sarcoidosis

From: Associations of serum long-chain fatty acids with multiple organ involvement in patients with sarcoidosis

 

Univariate analysis

Multivariate analysis

Set A

Set B

Set C

Variables

OR (95%CI)

P

OR (95%CI)

P

OR (95%CI)

P

OR (95%CI)

P

Agea

1.11 (1.06–1.16)

< 0.001

1.20 (1.10–1.31)

< 0.001

1.11 (1.05–1.18)

< 0.001

1.11 (1.06–1.16)

< 0.001

Sex, male

0.43 (0.19–0.98)

0.044

2.66 (0.44–16.30)

0.289

1.64 (0.38–7.01)

0.505

0.81 (0.26–2.59)

0.727

BMIb

0.97 (0.83–1.13)

0.671

      

n-3 PUFAs, high

0.05 (0.01–0.18)

< 0.001

0.01 (0.00-0.05)

< 0.001

    

n-6 PUFAs, high

0.06 (0.02–0.19)

< 0.001

  

0.03 (0.01–0.14)

< 0.001

  

n-3/n-6 ratio, high

0.34 (0.13–0.90)

0.030

    

0.25 (0.07–0.83)

0.023

SFAs, high

2.18 (0.85–5.61)

0.105

      

MUFAs, high

3.26 (1.14–9.34)

0.028

1.13 (0.15–8.71)

0.906

4.27 (0.87-21.00)

0.074

1.59 (0.38–6.58)

0.526

  1. The cutoff value for each long-chain fatty acid was determined by the Youden Index in receiver operating characteristic curve analysis (Supplementary Table 1). The Akaike Information criteria for Sets A, B, and C were 58.6, 76.1, and 96.4, respectively. OR, odds ratio; CI, confidence interval; BMI, body mass index; SFAs, saturated fatty acids; PUFAs, polyunsaturated fatty acids; MUFAs, monounsaturated fatty acids
  2. aPer 1-year increase
  3. bPer 1-kg/m2 increase
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