Fig. 2

miR-125b-5p reduces the sensitivity of NSCLC cells to DDP, thus leading to DDP resistance. A CCK8 assay was performed to detect DDP sensitivity in miR-125b-5p mimic/inhibitor-treated A549 cells upon stimulation with the indicated concentrations of DDP (0 μg/mL, 6.25 μg/mL). B, C Apoptosis analysis in A549 cells following transfection using miR-125b-5p mimic/inhibitor upon treatment with the indicated concentrations of DDP (0 μg/mL, 6.25 μg/mL). D CCK8 assay was performed to detect DDP resistance in miR-125b-5p mimic/inhibitor-treated A549/DDP cells upon stimulation with the indicated concentrations of DDP (0 μg/mL, 6.25 μg/mL). E, F Apoptosis analysis in A549/DDP cells following transfection with miR-125b-5p mimic/inhibitor upon treatment with the indicated concentrations of DDP. *p < 0.05, **p < 0.01, ***p < 0.05