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Fig. 5 | BMC Pulmonary Medicine

Fig. 5

From: miR-125b-5p upregulation by TRIM28 induces cisplatin resistance in non-small cell lung cancer through CREB1 inhibition

Fig. 5

miR-125b-5p lessens the sensitivity to DDP in vivo. A Representative images of xenografts generated by transfecting A549 cells using miR-125b-5p or empty lentiviruses. B Growth curve for xenograft produced by A549 cells with miR-125b-5p or empty lentiviruses in vivo. C Analysis of miR-125b-5p expression in xenografts by qRT-PCR. D CREB1 protein levels in xenografts by western blotting. E, F H&E staining and immunohistochemistry to detect pathological changes in xenografts. *p < 0.05; **p < 0.01

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BMC Pulmonary Medicine

ISSN: 1471-2466

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