Table 2 Respiratory Function
Parameter | ICU-Admission (N = 37) | MPT (N = 37) | 3 days post MPT (N = 32) | 10 days post MPT (n = 24) | 14 days post MPT (n = 22) | p-value | |
|---|---|---|---|---|---|---|---|
FiO2[%] | 77 ± 19 | 77 ± 22 | 62 ± 23 | 58 ± 26# (p = 0.024) | 67 ± 25 (N = 19) | 0.007 | |
paO2/FiO2 | 110 ± 54 | 116 ± 44 | 151 ± 65* (p = 0.034) | 151 ± 60* (p = 0.031) | 149 ± 64 (N = 21) | 0.006 | |
Tidal Volume [ml] | 480 ± 251 (N = 24) | 335 ± 259 (N = 24) | 403 ± 219 (N = 21) | 326 ± 172 (N = 19) | 294 ± 175§ (N = 15) | 0.044 | |
Driving Pressure [cmH2O] | 11 ± 8 (N = 24) | 13 ± 5 (N = 24) | 13 ± 6 (N = 20) | 15 ± 5 (N = 15) | 15 ± 5 (N = 11) | 0.202 | |
Compliance [ml/cmH2O] | 29 ± 29 (N = 21) | 21 ± 24 (N = 23) | 31 ± 38 (N = 17) | 16 ± 10 (N = 13) | 15 ± 12 (N = 10) | 0.112 | |
Mechanical Power [J/min] | 30 ± 27 (N = 24) | 20 ± 14(N = 24) | 23 ± 14 (N = 19) | 18 ± 13 (N = 12) | 16 ± 15 (N = 10) | 0.193 | |
CRP [mg/dl] | 8.6 ± 9.6 | 5.7 ± 7.3 | 2.9 ± 4.0*# (*p = 0.005; #p = 0.007) | 6.1 ± 7.7 | 5.5 ± 5.7 | 0.002 | |
Ventilation Mode n [%] | Spontaneous Breathing | 0 | 1 (3) | 0 | 5 (21) | 6 (27) | 0.001 |
O2-Insufflation | 3 (8) | 0 | 2 (6) | 0 | 1 (5) | ||
High-Flow O2 | 10 (27) | 12 (32) | 9 (28) | 4 (17) | 4 (18) | ||
PSV | 5 (14) | 9 (24) | 10 (31) | 6 (25) | 2 (9) | ||
PCV | 18 (49) | 14 (44) | 11 (34) | 8 (33) | 8 (36) | ||
APRV | 1 (3) | 1 (3) | 0 | 1 (4) | 1 (5) | ||
ECMO | 2 (5) | 19 (54) | 18 (51) | 16 (66) | 15 (68) |