Table 2 Characteristics of the recipients and intra-operative period depending on recipient’s pretransplantation BMI, univariate analysis

Characteristics of the recipients

 Age, recipient, years,

57[50–62]

51 [30–58]

57 [51–62]

57 [52–62]

< 0.001

 Male gender, n (%)

197 (65)

17 (41)

82 (63)

98 (74)

 < 0.001

 Height, cm, med [IQR]

170 [163–176]

162 [158–170]

170 [163–176]

172 [166–178]

 < 0.001

 Weight, Kg, med [IQR]

70 [58–80]

45 [43–50]

63 [56–70]

80 [75–89]

< 0.001

 BMI, Kg/m², med [IQR]

24 [21–27]

17 [16–18]

22 [20.9–24]

27.7 [9, 26–29]

< 0.001

 Smoking history, recipient, n (%)

208 (68)

22 (54)

89 (68)

97 (73)

0.068

Underlying disease

 Pulmonary fibrosis, n (%)

136 (45)

9 (22)

50 (38)

77 (58)

 < 0.001

 COPD, n (%)

92 (30)

11 (27)

45 (35)

36 (27)

0.36

Comorbidities

 Diabetes mellitus, n (%)

33 (11)

7 (17)

9 (7)

17 (13)

0.097

 High blood pressure, n (%)

77 (25)

7 (17)

24 (18)

46 (35)

0.005

 Hypercholesterolemia, n (%)

65 (21)

5 (12)

22 (17)

38 (29)

0.021

 Chronic ischaemic heart disease, n (%)

27 (9)

1 (2)

5 (4)

21 (16)

0.001

 Peripheral arterial disease, n (%)

13 (4)

1 (3)

4 (3)

8 (6)

0.53

Preoperative assessment

 Pulmonary hypertension, n (%)

149 (50)

16 (42)

65 (50)

68 (52)

0.57

 Dilatation of the right ventricle, n (%)

82 (27)

8 (20)

37 (29)

37 (28)

0.50

 Left ventricular ejection fraction, %, med [IQR]

63 [58–68]

62 [58–66]

64 [60–69]

62 [58–67]

0.47

 Serum creatinin, µmol/L, med [IQR]

68 [56–80]

53 [49–62]

68 [55–80]

72 [62–87]

 < 0.001

Clinical characteristics before surgery

 High flow oxygenotherapy before surgery, n (%)

50 (16)

7 (17)

18 (14)

25 (19)

0.55

 ECMO as bridge to LT, n (%)

23 (8)

5 (12)

5 (4)

13 (10)

0.075

 High emergency LT, n (%)

59 (19)

11 (27)

22 (17)

26 (20)

0.38

Characteristics of intra-operative period

 Bilateral LT, n (%)

210 (69)

30 (73)

94 (72)

86 (65)

0.34

 Retransplantation, n (%)

9 (3)

3 (7)

5 (4)

1 (1)

0.048

 Duration of surgical procedure, med [IQR]

420 [315–490]

420 [315–500]

420 [380–480]

420 [350–505]

0.78

 Peridural anesthesia, n (%)

197 (66)

24 (60)

88 (69)

85 (64)

0.55

 ECMO support during surgery, n (%)

220 (72)

27 (66)

86 (66)

107 (80)

0.021

 ECMO weaned in operating room, n (%)

130 (59)

18 (67)

54 (63)

58 (54)

0.34

 Cathecholamine support during surgery, n (%)

295 (97)

41 (100)

123 (95)

131 (98)

0.12

Transfusion during surgery, n (%)

 RBC transfusion

204 (68)

32 (78)

89 (69)

83 (63)

0.17

 0 RBC unit

98 (32)

9 (22)

42 (33)

47 (36)

0.30

 1–4 RBC units

148 (49)

20 (49)

64 (50)

64 (48)

  ≥ 5 RBC units

56 (19)

12 (29)

23 (18)

21 (16)

 FFP transfusion

188 (62)

30 (73)

74 (57)

84 (63)

0.16

 Platelet transfusion

64 (21)

11 (27)

31 (24)

22 (17)

0.22

 Vascular filling ≥ 2500 mL during surgery, n (%)

260 (86)

35 (85)

114 (88)

111 (85)

0.78